Results 151 to 160 of about 7,100,320 (319)

L'évaluation des effets d'une formation aux compétences d'aide et de son transfert en milieu réel

open access: yes, 2014
Les étudiants assistants sociaux se sentent-ils prêts à mener des entretiens avec des usagers lorsqu’ils entrent en stage de deuxième année baccalauréat ?
Degoedt, Aurelie, Chianura, Esther
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Uranium-lead age of monazite from granite of the gaysin complex (Ros-Tikits megablock of the Ukrainian shield

open access: yesМінеральні ресурси України, 2017
Haysin complex includes granitoids that form a continuous series of rocks: diorite – quartz diorite – granodiorite – amphibole–biotite granite – biotite granite – pink applet-pegmotoid granite.
L. M. Stepanyuk   +4 more
doaj  

Secteur de formation 19 : santé

open access: yes, 2008
Version 2007Titre de l'écran-titre (visionné le 6 janvier 2008)"Secteur de formation 19 : santé"Première éd., Montréal : Ministère de l'éducation, 2001 publiée sous le titre: Santé : soins infirmiers : programme d'études, 180 ...
Fons, Jean-Pierre   +10 more
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

La Formation sur mesure dans un contexte de partenariat : application d'un modèle d'intervention à trois situations d'apprentissage /

open access: yes, 1989
Notes bibliogr.
Lebel, Denis   +1 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

L'après formation : le défi

open access: yes, 2014
Que l’on soit dans le système éducatif ou en formation professionnelle, le retour de formation reste un moment délicat. En éducation,  ( formation initiale ou continue), il faut prouver lors d’un examen sur table que les connaissances académiques sont ...
Caroline Corvasce
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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