Results 161 to 170 of about 2,733,894 (315)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Formation control between leader and migratory follower tissues allows coordinated growth. [PDF]

Sci Adv
Kawanishi T, Sushida T, Tsai TY, Takeda H, Megason SG.   +4 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Fixed-Time Cooperative Formation Control of Heterogeneous Systems Under Multiple Constraints. [PDF]

Entropy (Basel)
Li Y, Zhao W, Zhu L, Zhang Z, Guo Y.
europepmc   +1 more source

Pi-stacking Enhances Stability, Scalability of Formation, Control over Flexibility and Circulation Time of Polymeric Filaments. [PDF]

Adv Nanobiomed Res, 2021
Li S, Bobbala S, Vincent MP, Modak M, Liu Y, Scott EA.   +5 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Fault-tolerant formation control of heterogeneous multi-agent systems with unknown inputs and external disturbances. [PDF]

Sci Rep
Li Y, Liu Y, Zhu L, Guo Y.
europepmc   +1 more source

Dolomite Reservoir Differences in Characteristics and Controlling Factors of Grainstone Shoal facies in Qixia Formation, Sichuan Basin [PDF]

Benjian Zhang, Hualing Ma, Xiaojie Huang, Xihua Zhang, Xiaohong Chen, Fujie Jiang, Chen Xie, Yangui Chen, Ran Liu, Wei Wang, Haitao Sun   +10 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

In-Orbit Optimal Safe Formation Control for Surrounding an Unknown Huge Target with Specific Structure by Using Relative Sensors Only. [PDF]

Sensors (Basel)
Wei B, Li C, Dang Z, Yue X.
europepmc   +1 more source