Results 71 to 80 of about 2,733,894 (315)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
To address the control challenges posed by increasingly complex mission scenarios, this paper aims to develop an advanced formation control and obstacle avoidance strategy for autonomous underwater vehicles (AUVs) in SE(3).
Qingzhe Zhen +3 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
This paper presents a comprehensive review of path planning in dynamic environments. This review covers the entire process, starting from obstacle detection techniques, through path-planning strategies, and also extending to formation control and ...
Nour AbuJabal +5 more
doaj +1 more source
CONCO2 RANDOMIZED CONTROLLED TRIAL INTERIM UPDATE: EMBRYO CULTURE IN A CONTINUOUS CARBON DIOXIDE SETTING DOES NOT NEGATIVELY IMPACT BLASTOCYST FORMATION RATES [PDF]
Julia G. Kim +8 more
openalex +1 more source
Adaptable Robot Formation Control: Adaptive and Predictive Formation Control of Autonomous Vehicles
The ability to use cooperative small vehicles is of interest in many applications. From material transportation to farming operations, the use of small machines achieving small tasks, but able to work together to complete larger tasks, permits us to rely on a unique kind of vehicle.
Guillet, A. +3 more
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Dynamic Density-Guided Method for Multi-Robot Formation Transformation
This paper addresses the formation control problem for ground mobile robot formations and proposes a formation transition method based on dynamic density guidance.
CAO Kai, CHEN Yangquan, LI Kang, CHEN Chaobo, YAN Kun, LIU Weichao
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

