Results 201 to 210 of about 2,199,507 (268)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

From loneliness to connection: the formation mechanism of loneliness, job search stress, and organizational belonging among students approaching graduation in a context of employment contraction. [PDF]

Front Psychol
Han L, Si X, Wang H, Leng X.
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Understanding the formation mechanism of crystalline hydrated polymorphs of carbonic acid from CO₂ clathrate hydrate. [PDF]

Chem Sci
Berni S, Scelta D, Romi S, Fanetti S, Alabarse F, Wehinger B, Bini R.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Analysis of Microstructure and Pore Formation Mechanism in Magnetic Pulse-Assisted Semi-Solid Brazed Joints of Cu/Al Tubes. [PDF]

Materials (Basel)
Rui Z, Huang S, Wang H.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Metabolomics and transcriptomics reveal the quality formation mechanism during the processing of black tea. [PDF]

NPJ Sci Food
Li M, Xu H, Chen H, Ding F, Li Q, Liu Z, Wang F, Jia X, Wu Y, Sun Y, Jin S.   +10 more
europepmc   +1 more source

Research Progress on Flavor Differences and the Formation Mechanism of Traditional Chinese Cereal Vinegar. [PDF]

Foods
Zhang J, Bian X, Zhao Y, Zhu Y, Bai J, Fan S, Xiao X.   +6 more
europepmc   +1 more source

[Differences in the formation mechanism of performance-based compensation in public hospitals with different administrative affiliations]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Zhang Y, Li Y, Ba T, Cai Z, Liu X, Feng W.   +5 more
europepmc   +1 more source