Results 131 to 140 of about 231,535 (312)
Computer and traditional tools in design activity: Experimental study on students of architecture
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2018 The worldwide emergence of computer tools in the field of architecture has evolved along with the great advance in digital technologies, extending to the whole process of the project.
Ouafa Saighi, Mohamed Salah Zerouala
doaj
, 1988 This is the first in a series of recollections by distinguished economists commissioned by the Banca Nazionale del Lavoro Quarterly Review. In it John Hicks reflects on his life, career and intellectual development.
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
, 1982 Six formations are defined : Landerneau Formation, with marine features, belongs to the terminal Pliocene /Lower Pleistocene ; the Quélonet and Plogoff Formations, which are not associated with periglacial formations, and the Langueux, La Haute-Ville and
Morzadec-Kerfourn, Marie +1 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 1979 (Table 16) Aluminum contents and element/aluminium ratios in sedimentary rocks of different formations drilled in holes of DSDP Legs 43 and ...
Murdmaa, Ivar O +11 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source