Results 221 to 230 of about 27,822 (264)

Digital Rights Activism in Multilevel Governance

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley   +1 more source

Evaluating global health programmes targeting under-5 mortality: problems and recommendations. [PDF]

open access: yesBMJ Glob Health
Kenny A   +9 more
europepmc   +1 more source

Building the Plane While Flying It: How Projects Serve to Implement, Pilot and Co‐Create EU Policy

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT This article theorizes how projectified governance enables bottom‐up policy shaping in the EU, using the European Universities Initiative (EUI) as a case study. It develops a framework that combines bottom‐up Europeanization with resource exchange theory to explain how project networks influence EU policymaking.
Alina Felder‐Stindt
wiley   +1 more source

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara   +7 more
wiley   +1 more source

Social inequalities in return-to-work among colorectal cancer survivors in Germany. [PDF]

open access: yesSupport Care Cancer
Soff J   +13 more
europepmc   +1 more source

Seizure relapse in new onset epilepsy: It is not always drug resistance

open access: yesEpilepsia, EarlyView.
Abstract Objective Seizure recurrence in new onset epilepsy (NOE) can result from various factors. Although drug ineffectiveness is frequently investigated, other causes—such as nonadherence, inadequate treatment, nonepileptic events (e.g., functional/dissociative), or acute symptomatic seizures—also impact patient outcomes.
Cecilia Catania   +11 more
wiley   +1 more source

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