Results 121 to 130 of about 2,527,861 (305)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Process and machine system development for the forming of miniature/micro sheet metal products [PDF]

open access: yes, 2007
This paper reports on the current development of the process for the forming of thin sheet-metal micro-parts (t < 50µm) and the corresponding machine system which is part of the research and technological development of an EU funded integrated project ...
Brockett, A.   +7 more
core   +2 more sources

Viscoelastic model for bending process of continuous fiber-reinforced thermoplastic sheets

open access: yesArchives of Mechanics
This paper presents an analysis of the bending process in thermoplastic sheets reinforced with unidirectional continuous fibers. To capture the material’s viscoelastic response during the bending process, a novel viscoelastic model is described based on ...
M.T. Abadi
doaj   +1 more source

Practical aspects of ecological competitiveness component of domestic hardboards enterprises-producers formation [PDF]

open access: yesMarketing i Menedžment Innovacij, 2012
The questions of ecological making competitiveness of products of woodworking industry domestic enterprises forming are considered in the article, necessity of ecological consciousness forming between all flakeboardss market participants is grounded.
O.A. Ovechkina, O.V. Maslosh
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Binary Forms

open access: yesProceedings of the National Academy of Sciences, 1940
Not ...
openaire   +4 more sources

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

EDM fine dressing formed diamond grinding wheel test

open access: yesJin'gangshi yu moliao moju gongcheng
ObjectivesIn today's information age, the semiconductor industry, as one of the core fields of modern science and technology, is booming at an astonishing speed.
FANG Zhou   +3 more
doaj  

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