Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecularly Imprinted Membranes for Selective Biomarker Recognition: Recent Advances and Emerging Strategies. [PDF]
Song Q, Van KV, Li X, Chen Z, Lv Y.
europepmc +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Surface-Enhanced Raman Spectroscopy Detection of Per- and Polyfluoroalkyl Substances in Aqueous Film-Forming Foams. [PDF]
Wang C +5 more
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Effect of Fe/Ni Microalloying on Interface Regulation of SiC/Al Composites: Molecular Dynamics Simulation and Experiments. [PDF]
Song T +5 more
europepmc +1 more source
Assessment of the feed additive consisting of L-cysteine hydrochloride monohydrate (2b920) for cats and dogs for the renewal of its authorisation (PRINOVA BENELUX AND FRANCE N.V). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +20 more
europepmc +1 more source
Double-diaphragm forming of highly aligned short-fibre preforms for complex composite parts. [PDF]
Gordon T +8 more
europepmc +1 more source

