Results 71 to 80 of about 2,831,132 (112)

Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome‐linked mutations

The FEBS Journal, EarlyView.
Fragile X messenger ribonucleoprotein 1 (FMRP) is a multidomain RNA‐binding protein associated with Fragile X Syndrome (FXS). We found that its N‐terminal structured region has an intrinsic propensity to undergo liquid–liquid phase separation and fibril formation. FXS‐associated mutations perturb protein stability and aggregation propensity, suggesting
Flavia Catalano, Alessandra Bigi, Francesca Troilo, Federica Gabriele, Gianluca Pistoia, Italia A. Asteriti, Francesco Angelucci, Giorgio Giardina, Fabrizio Chiti, Carlo Travaglini‐Allocatelli, Adele Di Matteo   +10 more
wiley   +1 more source

Formability Analysis of Fukui Stretch-Drawing and Square Cup Drawing Using Strain and Stress Based Forming Limit Curves

, 2017
In this work, the experimental and numerical analyses of Forming Limit Curve (FLC) and Forming Limit Stress Curve (FLSC) for Advanced High Strength Steel (AHSS) sheet, grade JAC780Y, are performed. Initially, the FLC is experimentally determined by means
Nopparat Seemuang, Taratip Chaimongkon, Sansot Panich   +2 more
core   +1 more source

CRISPR/Cas9‐Mediated Knockout of LbSP1 and LbSP5G1 Reveals Efficient Customization of Shoot Architecture in Black Goji Berry

Plant Biotechnology Journal, EarlyView.
ABSTRACT Goji is recognized as a nutritionally rich superfruit with medicinal and industrial importance. However, its inherently indeterminate growth habit causes asynchronous flowering and uneven fruit ripening, resulting in harvesting inefficiency with high labour costs and low fruit yield.
Fazal Rehman, Huanfang Liu, Yun Ma, Shaohua Zeng, Yan Wu, Yuan Zong, Chao Yang, Ying Wang   +7 more
wiley   +1 more source

Light Chain Monoclonal Gammopathy of Undetermined Significance: Diagnosis, Biology, and Clinical Management

European Journal of Haematology, Volume 117, Issue 5, Page 1159-1167, November 2026.
ABSTRACT Light chain monoclonal gammopathy of undetermined significance (LC‐MGUS) is defined by an abnormal serum free light chain ratio and elevated involved light chain in the absence of a detectable immunoglobulin heavy chain on immunofixation and of end‐organ damage attributable to a plasma cell disorder.
Sigurður Yngvi Kristinsson, Thórir Einarsson Long, Sigrún Thorsteinsdóttir   +2 more
wiley   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

The Experimental Determination of Parameters for the Modeling of the Stamping Process of AA6005C Aluminum Alloy

Alloys
This study provides the first complete and experimentally validated Yoshida–Uemori (Y–U) parameter set for AA6005C aluminum alloy, enabling accurate constitutive modeling for stamping simulations.
Luiza Emília Vila Nova Mazzoni, Fernanda Mariano Pereira, Estefani Alves da Silva Calabria, Luca de Paulo Ferreira, Alfredo Rocha de Faria, Tamires de Souza Nossa, Kahl Dick Zilnyk   +6 more
doaj   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, Volume 101, Issue 10, Page 2632-2651, October 2026.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

New components in genetic regulation of age‐dependent compound leaf architecture in pea

New Phytologist, Volume 252, Issue 2, Page 909-925, October 2026.
Compound leaf development in pea (Pisum sativum). Summary Pea (Pisum sativum L.) is a classic model for compound leaf development. Pea leaves typically consist of a proximal series of paired lateral leaflets substituted distally by filiform tendrils, and the number of lateral organ pairs increases with ontogeny.
Jacqueline K. Vander Schoor, Chantelle J. Beagley, Warwick Gill, Grégoire Aubert, Judith Burstin, Robert J. E. Wiltshire, Valérie Hecht, James L. Weller   +7 more
wiley   +1 more source

Experimental determination and numerical prediction of the dynamic forming limits of a press hardened steel

, 2021
Material characteristics such as yield strength, failure strain, strain hardening and strain rate sensitivity parameter are affected by loading speed. Therefore, the strain rate dependency of materials for plasticity and failure behavior is taken into ...
Tröster, Thomas, Schulz-Beenken, Anne Suse, Lian, Junhe, Weiß-Borkowski, Nathalie   +3 more
core   +1 more source

A Review of Sheet Metal Forming Evaluation of Advanced High-Strength Steels (AHSS)

Metals
This paper presents a review on the formability evaluation of AHSS, enhancing necking-based failure criteria limitations. Complementary fracture/damage constitutive modeling approaches specifically tailored to formability evaluation, validated through ...
Rui Pereira, Nuno Peixinho, Sérgio L. Costa   +2 more
doaj   +1 more source