Results 171 to 180 of about 2,375,841 (354)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Can You Succeed in Intentionally Deceiving Yourself?

Humana.Mente: Journal of Philosophical Studies, 2018
According to intentionalists, self-deceivers exercise the sort of control over their belief-forming processes that, in standard cases of interpersonal deception, the deceiver exercises over the deceived’s belief forming processes — they intentionally ...
Dion Scott-Kakures Scott-Kakures
doaj  

2022/2023 Hallmark University, Ijebi Itele Post UTME Admission/Direct Entry Form Out ☎ 2347065086538☎: 07065086538Dr Mrs. ANITA  Change Of Institution/Course form Is Out, Admin Contact: 07065086538 to Apply And ✔ For more information: On How To Process Your Admission  And For Admission Assistance Before The Closing Date

, 2022
James Ryan Mark
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Deformation Control of TC4 Titanium Alloy in Thin-Walled Hyperbolic Structures During Hot Forming Processes. [PDF]

Materials (Basel)
Zhang T, Xia J, Han X, Du L, Chen L, Han Y, Cao F, Wang D, Liu X.   +8 more
europepmc   +1 more source

(Admission Forms) Renaissance University 2022/2023,Application/Post Utme Form is Out Call +2347065086538-07065086538 Dr Mrs.Anita for more details on  Admission Processing, The minimum qualification for the Degree Programme is 5 credits including English Language, Mathematics and any three other relevant subjects at the WASC/NECO/NABTEB Examinations or their equivalent (at not more than 2 sittings)

, 2022
07065086538
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Notch signaling mediates between two pattern-forming processes during head regeneration in Hydra. [PDF]

Life Sci Alliance
Steichele M, Sauermann L, Pan Q, Moneer J, de la Porte A, Heß M, Mercker M, Strube C, Flaswinkel H, Jenewein M, Böttger A.   +10 more
europepmc   +1 more source

Microbially Mediated Ore-Forming Processes and Cell Mineralization. [PDF]

Front Microbiol, 2019
Polgári M, Gyollai I, Fintor K, Horváth H, Pál-Molnár E, Biondi JC.   +5 more
europepmc   +1 more source