Results 231 to 240 of about 2,360,139 (304)

Evolutionary bioenergetics of sporulation. [PDF]

Proc Natl Acad Sci U S A
Karakoç C, Shoemaker WR, Lennon JT.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Modeling the Friction Behavior of Low-Carbon Steel Sheets Using Various Machine Learning Algorithms Based on Strip Drawing Test Data. [PDF]

Materials (Basel)
Trzepieciński T.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Pharmacoepigenomics in Personalized Medicine: A Hypothesis-Generating Approach to Introduce CpG-PGx SNPs as New Candidates for a Systematic Insight into Genomic-Epigenomic-Phenomic-Pharmacogenomics (G-E-Ph-PGx) Axis. [PDF]

J Pers Med
Sharafshah A, Blum K, Lewandrowski KU, Elman I, Fuehrlein BS, Baron D, Pinhasov A, Thanos PK, Fiorelli RKA, Schmidt SL, Gardner EL, Lorio MP, Lewandrowski APL, Gold MS.   +13 more
europepmc   +1 more source

Optimisation of Forming Processes

, 2003
openaire   +6 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Isotopic evidence for volatile loss driven by South Pole-Aitken basin-forming impact. [PDF]

Proc Natl Acad Sci U S A
Tian HC, Zhang C, Li WJ, Xue D, Wang J, Yang W, Liu YH, Lin Y, Li XH, Wu FY.   +9 more
europepmc   +1 more source

Chemical and Thermal Stability of Sr_1.9VMoO_6-δ: Implications for High Temperature Energy Conversion Applications. [PDF]

ACS Omega
Samuel BJ, Esakoff JA, Heywood SK, Sofie SW, Walker RA.   +4 more
europepmc   +1 more source