Results 51 to 60 of about 772,809 (315)
The use of ultra-high-strength aluminum alloys plays a key role in future lightweight construction in the field of electromobility. In particular, high-strength 7000 series aluminum alloys are excellent candidates for lightweight structures due to their ...
S. Völkers +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Microstructure Evolution and Material Flow of Steel in Semi-solid Forming Process [PDF]
The present study aims to identify and characterize the development of microstructure and deformation characteristics of steel grades in semi-solid state which is affected by the change in morphologies of microstructure at high temperature ...
GU, Guochao +4 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Modelling and Simulation of Sheet Metal Forming Processes
Numerical simulation of sheet metal forming processes has become an indispensable tool for the design of components and their forming process, in industries ranging from the automotive, to the aeronautics, packing and household appliances [...
Marta C. Oliveira +3 more
core +1 more source
This study investigates the influence of key heat treatment parameters on the microstructure and mechanical properties of the powder metallurgy tool steel Vanadis 60.
Florentino Alvarez-Antolin +1 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Induction Heating Validation of Dieless Single-Point Incremental Forming of AHSS
Advanced high-strength steel (AHSS) is subject to a high deformation in geometry due to spring-back and high forces during forming. Therefore, dieless single-point incremental forming supported by induction heating was introduced.
Amar Al-Obaidi +2 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

