Results 51 to 60 of about 772,809 (315)

On the influence of in situ sound wave superposition on the microstructure of laser welded 7000 aluminum alloys

open access: yesJournal of Advanced Joining Processes, 2020
The use of ultra-high-strength aluminum alloys plays a key role in future lightweight construction in the field of electromobility. In particular, high-strength 7000 series aluminum alloys are excellent candidates for lightweight structures due to their ...
S. Völkers   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Microstructure Evolution and Material Flow of Steel in Semi-solid Forming Process [PDF]

open access: yes, 2011
The present study aims to identify and characterize the development of microstructure and deformation characteristics of steel grades in semi-solid state which is affected by the change in morphologies of microstructure at high temperature ...
GU, Guochao   +4 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Modelling and Simulation of Sheet Metal Forming Processes

open access: yes, 2019
Numerical simulation of sheet metal forming processes has become an indispensable tool for the design of components and their forming process, in industries ranging from the automotive, to the aeronautics, packing and household appliances [...
Marta C. Oliveira   +3 more
core   +1 more source

Effect of Heat Treatment on the Microstructure and Mechanical Properties of Vanadis 60 Steel: A Statistical Design Approach

open access: yesSolids
This study investigates the influence of key heat treatment parameters on the microstructure and mechanical properties of the powder metallurgy tool steel Vanadis 60.
Florentino Alvarez-Antolin   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Induction Heating Validation of Dieless Single-Point Incremental Forming of AHSS

open access: yesJournal of Manufacturing and Materials Processing, 2017
Advanced high-strength steel (AHSS) is subject to a high deformation in geometry due to spring-back and high forces during forming. Therefore, dieless single-point incremental forming supported by induction heating was introduced.
Amar Al-Obaidi   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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