Results 191 to 200 of about 1,434,591 (267)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Understanding Pride in Eating Disorders and Disordered Eating Behaviors: A PRISMA-Informed Scoping Review. [PDF]

J Clin Med
Del Conte E, Tecuta L, Tomba E.
europepmc   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Effect of doula support during labor on perineal and anal sphincter injury in primiparous women. [PDF]

Arch Gynecol Obstet
Baruch Y, Amikam U, Attali E, Gold R, Groutz A, Yogev Y, Michaan N.   +6 more
europepmc   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Identifying Gaps and Challenges in Acute Hepatitis B Surveillance in the Country of Georgia: Comprehensive Surveillance System Evaluation.

JMIR Public Health Surveill
Karichashvili L, Galdavadze K, Zakhashvili K, Tsereteli M, Ruadze E, Surguladze S, Stefanoff P.   +6 more
europepmc   +1 more source

Young People With and Without Intellectual Disability Accessing Mental Health Services: Evaluating Psychosocial Functioning Outcomes Using Electronic Health Records. [PDF]

J Intellect Disabil Res
Pan ZS, Schuengel C, Coughlan B, Bakkum L, Woolgar M, Carman S, Duschinsky R.   +6 more
europepmc   +1 more source

Funding guidance for young people 2012/13 : funding regulations [PDF]

, 2012

core  

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Estimating the efficacy of isometric handgrip training to lower resting blood pressure in patients with stage 1 hypertension in Eastern Uganda compared to standard of care: study protocol for a randomized controlled trial. [PDF]

Trials
Zinszer K, Isabirye H, Kalumuna C, Charland K, Katureebe A, Da Torre MB, van Wyk PM, Nabirye S, Stone J, Levy P, McGowan C.   +10 more
europepmc   +1 more source