Results 41 to 50 of about 1,119,114 (286)

Minimization for Generalized Boolean Formulas [PDF]

open access: yes, 2011
The minimization problem for propositional formulas is an important optimization problem in the second level of the polynomial hierarchy. In general, the problem is Sigma-2-complete under Turing reductions, but restricted versions are tractable. We study
Hemaspaandra, Edith, Schnoor, Henning
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

23-gauge vitrectomy with intraocular foreign body removal via the limbus: An alternative approach for select cases

open access: yesIndian Journal of Ophthalmology, 2014
Purpose: To study the outcome of removal of retained intraocular foreign bodies (RIOFBs) via limbus using 23-gauge transconjunctival sutureless vitrectomy (TSV).
Ramandeep Singh   +3 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A Multi-Frequency Patch Antenna With Double Sided Parallel Strip Line Periodic Structure

open access: yesIEEE Access, 2020
A multi-frequency patch antenna with double-sided parallel-strip line (DSPSL) periodic offset structure is proposed. The designed antenna consists of a simple rectangular patch as well as an embedded one-dimensional DSPSL periodic offset structure, which
Kebin Liu   +5 more
doaj   +1 more source

Discriminant Formulas and Applications

open access: yes, 2016
We solve two conjectures of Ceken-Palmieri-Wang-Zhang concerning discriminants and give some applications.Comment: 33 pages. Edit: In version 2, we removed the hypothesis that 1-q is invertible in Theorem 0.
Chan, Kenneth   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

¿Es [formula] igual a [formula] + [formula]?

open access: yesMomento, 1995
En este artículo analizamos desde un punto de vista crítico una interpretación errónea de la derivada respecto al tiempo de la cantidad de movimiento lineal en la segunda ley de Newton, frecuentemente enseñada en los cursos elementales de Mecánica.
Zalamea G., Eduardo   +3 more
openaire   +2 more sources

Cauchy non-integral formulas [PDF]

open access: yes, 2012
We study certain generalized Cauchy integral formulas for gradients of solutions to second order divergence form elliptic systems, which appeared in recent work by P. Auscher and A. Ros\'en.
Rosén, Andreas
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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