Results 61 to 70 of about 9,514 (190)

DRIVE v3: Command Line Application for Identity‐by‐Descent Haplotype Clustering in Large Biobank Scale Data

Genetic Epidemiology, Volume 50, Issue 5, July 2026.
ABSTRACT There is a need for genetic analytical methods that integrate multi‐individual identity‐by‐descent (IBD) tools with phenotypic enrichment testing to discover novel shared haplotypes contributing to disease traits. Existing tools are designed to identify IBD sharing and leave interpretation and phenotype association tests to further analyses ...
James T. Baker, Hung‐Hsin Chen, Grahame F. Evans, Alyssa C. Scartozzi, Ryan J. Bohlender, Chad D. Huff, Quinn S. Wells, David C. Samuels, Jennifer E. Below   +8 more
wiley   +1 more source

Development and Use of a Population Pharmacokinetic Model for Characterizing the Pharmacokinetics of Vonoprazan in Pediatric Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
Sequential population pharmacokinetic (PopPK) model development for vonoprazan in pediatric subjects. Adult data were used to establish the initial model, which was sequentially updated with data from adolescents (Study VPED‐102) and children (Study VPED‐103) to characterize vonoprazan pharmacokinetics and support pediatric dose selection.
Darcy J. Mulford, Axel Facius, Galen Witt, Colin W. Howden, Thomas Wagner, Eckhard Leifke, Carmelo Scarpignato   +6 more
wiley   +1 more source

Integration of Deep Neural Network‐Based Boundary Layer Subgrid Frictional Effects Into the Momentum Equation Constraint of WRFDA EnVar to Improve Tropical Cyclone Forecasts

Journal of Advances in Modeling Earth Systems, Volume 18, Issue 7, July 2026.
Abstract The incorporation of appropriate dynamic constraints in data assimilation (DA) is highly important for improving the forecasting of disastrous weather. It is often challenging to describe subgrid physical processes with strong nonlinearity and discontinuity in dynamic constraints because of difficulties in tangent linear and adjoint ...
Xin Li, Jian‐Feng Gu, Yi Li, Yu Zheng, Yuan Zhuang, Shiwei Sun, Zhiqiang Cui   +6 more
wiley   +1 more source

PySSM: A Python Module for Bayesian Inference of Linear Gaussian State Space Models

Journal of Statistical Software, 2014
PySSM is a Python package that has been developed for the analysis of time series using linear Gaussian state space models. PySSM is easy to use; models can be set up quickly and efficiently and a variety of different settings are available to the user ...
Christopher Strickland, Robert Burdett, Kerrie Mengersen, Robert Denham   +3 more
doaj   +1 more source

On the Variability of the Agulhas Bank Circulation

Journal of Geophysical Research: Oceans, Volume 131, Issue 7, July 2026.
Abstract This modeling study investigates the variability of the Agulhas Bank (AB) circulation, focusing on its connections to the local wind forcing and the Agulhas Current (AC) as well as to teleconnections to the tropical South Atlantic. The mean AB circulation is dominated by a westward flow composed of a coastal jet, an outer‐shelf flow influenced
V. Combes, R. P. Matano
wiley   +1 more source

Changes in Arctic Sea Ice Lead Width Distribution: Model Development and Experiments

Journal of Geophysical Research: Oceans, Volume 131, Issue 7, July 2026.
Abstract Sea ice leads play a significant role in the atmosphere‐sea ice‐ocean systems. Model representation of leads of varying widths is desirable to enhance our understanding of the behavior of leads and associated processes. We have developed a lead width distribution (LWD) conservation equation to explicitly simulate the evolution of leads of ...
Jinlun Zhang, Zheng Liu, Axel Schweiger, Harry Stern   +3 more
wiley   +1 more source

The seven ages of Fortran

Journal of Computer Science and Technology, 2011
When IBM's John Backus first developed the Fortran programming language, back in 1957, he certainly never dreamt that it would become a world-wide success and still be going strong many years later.
Michael Metcalf
doaj  

Studying the Process of Optimal Positioning of Field Concentrator in the Microwave Applicator [PDF]

Journal of Electrical and Electronics Engineering, 2008
The heating in a microwave field with ceramicmaterials at the frequency of 2,45 GHz providessolutions for creating some applicators with fieldconcentrator made up of ceramic material.In this paperwe present a study concerning the optimal positioningof ...
Ilie Stoichescu, Radu Sebeşan, Teodor Leuca   +2 more
doaj  

Validation of the IRI‐2020 Model Topside Ionosphere Options Through COSMIC‐1 and COSMIC‐2 Radio Occultation Profiles Collocated With Ionosonde Observations

Space Weather, Volume 24, Issue 7, July 2026.
Abstract This study validates the four topside ionosphere model options included in the latest release of the International Reference Ionosphere (IRI‐2020) model: IRI‐2001, IRI‐2001cor, IRI‐NeQuick, and the default IRI‐COR2. To assess their ability to reproduce the topside profile while minimizing uncertainties associated with F2‐layer peak modeling ...
A. Pignalberi, H. Haralambous, D. Bilitza, P. Coïsson, B. Nava, M. Pezzopane, F. Prol, A. Smirnov, D. R. Themens, C. Xiong   +9 more
wiley   +1 more source

Fortran Refactorings for Legacy Systems

Journal of Computer Science and Technology, 2011
This thesis is based on a certain type of legacy software that came from scientific research. Scientists have become one of the most important legacy code producers for many reasons.
Mariano Méndez
doaj