Results 41 to 50 of about 2,755,039 (251)

A New Hard Switching Bidirectional Converter With High Power Density [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2010
In this paper, a new isolated dc-dc bidirectional converter is proposed. This converter consists of two transformers (flyback and forward) and only one switch in primary side and one switch in secondary side of transformers.
Bahador Fani   +2 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Treatment Adherence and Adherence Patterns of Tofacitinib and Self‐Injectable TNFi Use in People with Rheumatoid Arthritis

open access: yesACR Open Rheumatology
Objective To assess tofacitinib and self‐injectable tumor necrosis factor inhibitor (TNFi) adherence using the Medication Event Monitoring System (MEMS) and characterize association with adherence in patients with rheumatoid arthritis (RA).
Kaleb Michaud   +5 more
doaj   +1 more source

Algorithms for Hidden Markov Models Restricted to Occurrences of Regular Expressions

open access: yesBiology, 2013
Hidden Markov Models (HMMs) are widely used probabilistic models, particularly for annotating sequential data with an underlying hidden structure. Patterns in the annotation are often more relevant to study than the hidden structure itself. A typical HMM
Thomas Mailund   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

DÖVİZ FUTURE SÖZLEŞMESİ, FIKHÎ BOYUTU VE ALTERNATİFLERİ

open access: yesFırat Üniversitesi İlahiyat Fakültesi Dergisi, 2021
Bu çalışma dört ana başlıktan oluşmaktadır. Birinci başlıkta Esnâf-ı Sitte hadisi bağlamında fakîhlerin sarf tanımı ve sarfın sıhhat şartları ile ilgili görüşleri ele alınmaktadır.
Zeynelabidin Hayat
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

INFORMATION FLOW BETWEEN THE US DOLLAR-RUPIAH EXCHANGE RATES

open access: yesBuletin Ekonomi Moneter dan Perbankan, 2020
This study investigates the information flow between non-deliverable forward (NDF), spot, and forward US dollar–rupiah exchange rates during the post-Quantitative Easing (QE) period. Our results show a unidirectional information flow from NDF to the spot
Wee-Yeap Lau, Tien-Ming Yip
doaj   +1 more source

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