Results 171 to 180 of about 357,951 (287)

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

open access: yesAdvanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang   +14 more
wiley   +1 more source

Correction to: Deucravacitinib Improves Patient-Reported Outcomes in Patients with Moderate to Severe Psoriasis: Results from the Phase 3 Randomized POETYK PSO-1 and PSO-2 Trials. [PDF]

open access: yesDermatol Ther (Heidelb)
Armstrong AW   +11 more
europepmc   +1 more source

Non‐Invasive Diagnosis of Chronic Myocardial Infarction via Composite In‐Silico‐Human Data Learning

open access: yesAdvanced Science, EarlyView.
This study presents a non‐invasive machine learning model to identify infarct regions in the left ventricle using cardiac strain data. By combining rodent‐based simulated data with limited human data, the model achieves high accuracy in predicting infarct size and location without the need for gadolinium contrast agents, offering a promising ...
Rana Raza Mehdi   +7 more
wiley   +1 more source

EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells

open access: yesAdvanced Science, EarlyView.
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li   +15 more
wiley   +1 more source

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