Results 121 to 130 of about 26,933 (290)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Evaluation of the Forward Head Posture, its association with Neck Pain & Quality of life of Female DPT Students

Journal Riphah College of Rehabilitation Sciences, 2016
Background: Craniovertebral angle is the landmark for assessment of head and neck postures. The angle is significantly smaller in subjects with neck pain.
Abrish Habib Abbasi, Mamoona Aslam, Tehseen Ashraf, Arshad Nawaz Malik   +3 more
doaj  

Relationship between forward head posture with neck pain and disability

, 2019
Introduction: One of the most common poor postures in the head and neck region is the forward head posture (FHP). It seems that improper posture for a long period of time causes abnormal physiological load on the neck.
Raoofi, Zeinab, Emrani, Anita, Sarrafzadeh, Javad, Ghorbanpour, Arsalan   +3 more
core   +1 more source

Learning Moisture‐Induced Damage From Vision: Diffusion Models for Real‐Time Monitoring of Additive Manufacturing Processes

Advanced Science, EarlyView.
We introduce a vision‐based real‐time monitoring system for additive manufacturing that detects subtle moisture‐induced degradation via a diffusion model‐based framework. The approach enables nondestructive assessment of moisture‐induced damage level and mechanical performance and establishes a practical route toward more intelligent, reliable, and ...
Jiyoung Jung, Yuna Yoo, Dharneedar Ravichandran, Dahyun Daniel Lim, Grace X. Gu   +4 more
wiley   +1 more source

ARRATIVE REVIEW : HUBUNGAN WAKTU PENGGUNAAN SMARTPHONE TERHADAP FORWARD HEAD POSTURE PADA REMAJA [PDF]

, 2020
Latar belakang :.Dewasa ini angka pengguna gadget terutama smartphone di dunia setiap tahunnya terus mangalami peningkatan. Indonesia merupakan salah satu negara dengan pertumbuhan terbesar di bawah china dan India..
Malika Arbi Yunistiana, 1610301164, Luluk Rosida, S.ST., M.KM. Kes, Ika Fitri Wulan Dhari, SSt.Ft, M.Erg   +2 more
core  

A Biomimetic Dual‐Targeting Nano‐APA‐Editor Reprograms the 3'UTR Landscape for Tongue Squamous Cell Carcinoma Therapy

Advanced Science, EarlyView.
This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao, Bin Gu, Hui Zhao, Kun Tan, Qin Zhao, Zhengjun Shang   +5 more
wiley   +1 more source

The Addition Of Pressure Biofeedback Unit In Forward Head Exercise Is Better On Improving Neck Alignment Asymptomatic Forward Head Posture

Asymptomatic forward head posture is a chronic condition without symptoms. Improvement in neck alignment can be enhanced by adding a pressure biofeedback unit to forward head exercises. The aim of this study was to determine if the addition of a pressure
I Nyoman Adi Putra, I Gede Eka Juli Prasana, Muliarta, I Ketut Suyasa, I Made Krisna Dinata, Wahyuddin   +5 more
core   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source