Results 31 to 40 of about 802,446 (258)
A note on the direction of the transcritical bifurcation in epidemic models
Nonlinear Analysis, 2015 In classical epidemic models, it is common to observe that a disease-free equilibrium looses its stability for R0=1 and a transcritical bifurcation takes place.
Bruno Buonomo
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IEEE Access, 2023 Machine learning (ML) has gained recognition as an efficient and robust technique to realize the solution of electromagnetic forward and inverse problems.
Debanjali Sarkar +3 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi +6 more
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Forward charm-production models and prompt neutrinos at IceCube
Journal of High Energy Physics, 2018 We investigate the prompt neutrino background at IceCube, as determined from forward charm. We consider the role of intrinsic charm and of a recombination model and show that the contribution of these mechanisms is at most a factor two.
Atri Bhattacharya, J. R. Cudell
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
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Earth and Space ScienceInversions of interseismic geodetic surface velocities often cannot uniquely resolve the three‐dimensional slip‐rate distribution along closely spaced faults.
H. Elston +3 more
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Emerging organoid models: leaping forward in cancer research
Journal of Hematology & Oncology, 2019 Cancer heterogeneity is regarded as the main reason for the failure of conventional cancer therapy. The ability to reconstruct intra- and interpatient heterogeneity in cancer models is crucial for understanding cancer biology as well as for developing ...
Han Fan, Utkan Demirci, Pu Chen
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