Results 171 to 180 of about 676,463 (285)

The Challenge of Handling Structured Missingness in Integrated Data Sources

Advanced Intelligent Discovery, EarlyView.
As data integration becomes ever more prevalent, a new research question that emerges is how to handle missing values that will inevitably arise in these large‐scale integrated databases? This missingness can be described as structured missingness, encompassing scenarios involving multivariate missingness mechanisms and deterministic, nonrandom ...
James Jackson, Marius Hofert, Eleni‐Rosalina Andrinopoulou, Niels Hagenbuch, Sarah McGough, Chris Harbron, Robin Mitra   +6 more
wiley   +1 more source

Toward Knowledge‐Guided AI for Inverse Design in Manufacturing: A Perspective on Domain, Physics, and Human–AI Synergy

Advanced Intelligent Discovery, EarlyView.
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee, Hyeonbin Moon, Junhyeong Lee, Seunghwa Ryu   +3 more
wiley   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Artificial intelligence and genomic data privacy: Balancing innovation with security. [PDF]

Mol Biol Res Commun
Kohan L.
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Context Awareness and Human–Robot Interaction Optimization for Museum Intelligent Guide Robot

Advanced Intelligent Systems, EarlyView.
This study presents a context‐aware human–robot interaction framework designed for intelligent museum guide robots. The system features a three‐layer architecture—perception, understanding, and behavior execution—that enables adaptive and meaningful interactions with museum visitors.
Anna Zou, Yue Meng, Shijing Tong
wiley   +1 more source

The role of trust and relationship building in the ethical recruitment of youth living with HIV in research: perspectives from Kenyan youth living with HIV, their caregivers and subject matter experts. [PDF]

BMC Med Ethics
Chory A, Boal A, Nyandiko W, Aluoch J, Scanlon M, Gillette E, Koros H, Ashimosi C, Beigon W, Munyoro D, Lidweye J, Nyagaya J, DeLong A, Kantor R, Naanyu V, Vreeman R.   +15 more
europepmc   +1 more source

Electroencephalogram‐Driven Recognition of Parkinson's Disease Through a Mycelium‐Inspired Memristive Reservoir Computing Circuit

Advanced Intelligent Systems, EarlyView.
This work presents a bio‐inspired computing framework for Parkinson's disease analog recognition using electroencephalogram signals. Temporally encoded EEG features stimulate a mycelium‐inspired memristive reservoir, where disease‐related patterns emerge through physical spatiotemporal dynamics.
Ioannis K. Chatzipaschalis, Ioannis Tompris, Pantelis Fraidakis, Iosif‐Angelos Fyrigos, Antonio Rubio, Georgios Ch. Sirakoulis   +5 more
wiley   +1 more source

A Lightweight Authentication and Key Distribution Protocol for XR Glasses Using PUF and Cloud-Assisted ECC. [PDF]

Sensors (Basel)
Cha W, Lee HJ, Kook S, Kim K, Won D.
europepmc   +1 more source