Two Novel S‐methyltransferases Confer Dimethylsulfide Production in Actinomycetota
This study identifies two novel S‐adenosine‐methionine‐dependent methyltransferases, MddM1 and MddM2, in actinomycetes from the Mariana Trench. These enzymes can convert toxic hydrogen sulfide (H2S) and methanethiol (MeSH) into dimethylsulfide (DMS), serving as a cellular detoxification and oxidative stress response.
Ruihong Guo +11 more
wiley +1 more source
Advanced investing with deep learning for risk-aligned portfolio optimization. [PDF]
Nguyen MD.
europepmc +1 more source
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing +7 more
wiley +1 more source
Distribution Approach to Local Volatility for European Options in the Merton Model with Stochastic Interest Rates. [PDF]
Nowak P, Gatarek D.
europepmc +1 more source
Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao +5 more
wiley +1 more source
"Good and bad investments" in public health stocks amid the COVID-19 shock: evidence from a transformer-based model. [PDF]
Zhao D, Li Y, Gu R.
europepmc +1 more source
A field‐effect transistor incorporating type‐I InP/ZnSe core–shell quantum dots demonstrates light‐ and gate‐tunable synaptic plasticity. By leveraging field‐assisted photoinduced charge trapping, the device emulates essential neuromorphic functions, including paired‐pulse facilitation, memory consolidation, and classical conditioning.
Guohao Wen +8 more
wiley +1 more source
An empirical evaluation of fuzzy bidirectional long short-term memory with soft computing based decision-making model for predicting volatility of cryptocurrencies. [PDF]
Ragab M.
europepmc +1 more source
The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification
Plant trichomes are not just simple hairs but metabolic powerhouses shaped by complex genetic programs. While the MYB‐bHLH‐WD40 module is well studied in Arabidopsis, recent findings reveal that HD‐Zip IV transcription factors drive multicellular and glandular trichome development through dose‐dependent mechanisms.
Meng Li +3 more
wiley +1 more source

