Results 141 to 150 of about 5,126 (291)
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Amendment methodology reasoning of market strategy a freight forwarder company
, 2015 У статті досліджується проблема забезпечення конкурентоспроможності вітчизняних транспортно-експедиторських компаній в умовах невизначеності зовнішнього середовища їх функціонування, яка викликає необхідність вдосконалення методів та розвитку ...
Гладковська, Валентина Валеріївна +1 more
core
Lightweight Differentiated Transmission Based on Fuzzy and Random Modeling in Underwater Acoustic Sensor Networks. [PDF]
Sensors (Basel), 2023 Cao J, Dou J, Liu J, Li H, Chen H.
europepmc +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Design of forwarder list selection scheme in opportunistic routing protocol
, 2008 Unlike traditional wireless routing protocols which use a single fixed path, opportunistic routing explicitly takes advantage of the broadcast nature of wireless communications by using a set of forwarders to opportunistically perform packet forwarding ...
Chen, Wei, Li, Yanhua, Zhang, Zhi-Li
core
Void Avoiding Opportunistic Routing Protocols for Underwater Wireless Sensor Networks: A Survey. [PDF]
Sensors (Basel), 2022 Mhemed R, Phillips W, Comeau F, Aslam N.
europepmc +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Improved Forward-Forward Contrastive Learning
CoRRThe backpropagation algorithm, or backprop, is a widely utilized optimization technique in deep learning. While there's growing evidence suggesting that models trained with backprop can accurately explain neuronal data, no backprop-like method has yet been discovered in the biological brain for learning.
openaire +3 more sources
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source