Results 111 to 120 of about 295,278 (291)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Securitization of Longevity and Mortality Risk [PDF]
This paper deals with Alternative Risk Transfer (ART) through the securitization of longevity and mortality risks in pension plans and commercial life insurance. Various types of such mortality-linked securities are described (e.g., CATM bonds, longevity
Tomas Cipra
core
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Guest Editorial: Moving Forwards ... [PDF]
Peter J. Rimmer
doaj +1 more source
Looking Forwards and Looking Back (Editorial)
Welcome to the seventh volume of Evidence Based Library and Information Practice. This is my first issue in my new role of Editor-in-Chief, and I’m honoured and delighted to take over the position.
Alison Brettle
doaj
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
O rugby sevens é jogado em um campo com as medidas oficias do rugby-15 e com duração de dois tempos de 7 minutos entre equipes com apenas 7 jogadores cada.
Nuno Manuel Frade de Sousa +4 more
doaj
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
O rugby sevens é jogado em um campo com as medidas oficias do rugby-15 e com duração de dois tempos de 7 minutos entre equipes com apenas 7 jogadores cada.
Nuno Manuel Frade de Sousa +5 more
doaj
We evaluated associations between muscle phenotype, positional role, and on‐ice performance in male U20 Danish national team ice hockey players. Sixteen players (10 forwards, six defensemen) participated in a game with activity tracking.
Jeppe F. Vigh‐Larsen +10 more
doaj +1 more source

