Results 101 to 110 of about 32,170 (168)

Real-World Comparison of Maribavir to Foscarnet for the Treatment of Cytomegalovirus in Solid Organ and Hematopoietic Stem Cell Transplant Recipients. [PDF]

Viruses
Ogawa L, Morinishi C, Multani A, Gaynor P, Beaird OE, Pham C, Schaenman JM.   +6 more
europepmc   +1 more source

Status epilepticus in older adults: A critical review

Epilepsia, EarlyView.
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward, Michael J. Armahizer, Tina I. Wang, Neeraj Badjatia, Emily L. Johnson, Emily J. Gilmore   +5 more
wiley   +1 more source

Investigation of the Effects of Fosfomycin in Kidney Damage Caused by CLP-Induced Sepsis. [PDF]

Life (Basel)
Yildiz IE, Mercantepe T, Bahceci I, Arpa M, Batcik S, Yildiz Y, Tumkaya L.   +6 more
europepmc   +1 more source

Estrogen receptors and extracellular matrix: the critical interplay in cancer development and progression

The FEBS Journal, Volume 292, Issue 7, Page 1558-1572, April 2025.
Breast cancer is a complex disease significantly influenced by estrogen receptors (ERs) and the extracellular matrix (ECM), both of which are critical in shaping tumor behavior. ERα and ERβ modulate cancer progression and therapeutic response with their interactions intricately linked to ECM dynamics.
Sylvia Mangani, Zoi Piperigkou, Nikolaos E. Koletsis, Paraskevi Ioannou, Nikos K. Karamanos   +4 more
wiley   +1 more source

Anti-central fatigue effects of myelophil in 5-HTergic hyperactivity mice model. [PDF]

BMC Complement Med Ther
Kang JY, Baek DC, Lee JS, Son CG.
europepmc   +1 more source

The universal role of adaptive transcription in health and disease

The FEBS Journal, EarlyView.
Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley   +1 more source

High prevalence of plasmid-mediated Fosfomycin resistance in waterfowl-derived <i>Escherichia coli</i> strains: insights into genetic context and transmission dynamics in China. [PDF]

Front Vet Sci
Zhang S, Yang J, Yang Q, Li Q, Zhong Z, Wang M, Jia R, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Huang J, Ou X, Sun D, Tian B, Wu Z, He Y, Cheng A.   +19 more
europepmc   +1 more source

Pharmacological manipulation of liver fibrosis progression using novel HDAC6 inhibitors

The FEBS Journal, EarlyView.
Chronic liver injury can lead to severe conditions such as cirrhosis and liver cancer. Unfortunately, there are no effective treatments to halt or reverse liver fibrosis, which makes new therapeutic strategies essential. This study focuses on the role of histone deacetylases (HDACs) in liver fibrosis, particularly HDAC6.
Maria Teresa Borrello, Dusan Ruzic, Hannah Paish, Eleanor Graham, Amy L. Collins, Rebecca Scott, Sam Higginbotham, Branko Radovic, Glyn Nelson, David Bulmer, Lee A. Borthwick, Stuart M. Robinson, Jeremy French, John Moir, Steve A. White, Colin Wilson, Sanjay Pandanaboyana, John Hammond, Rohan Thakkar, Wasfi Alrawashdeh, Rodrigo Figueiredo, Milos Petkovic, Katarina Nikolic, Fiona Oakley, Derek A. Mann, Jelena Mann   +25 more
wiley   +1 more source

ROR1 facilitates glioblastoma growth via stabilizing GRB2 to promote c-Fos expression in glioma stem cells. [PDF]

Neuro Oncol
Zhu H, Cheng L, Liu D, Ma X, Chen Z, Fan H, Li R, Zhang Y, Mi H, Li J, Zhang S, Yu X, Shu K.   +12 more
europepmc   +1 more source

Transcriptomic signatures of host immune responses in aphthous ulcers, the earliest lesions of Crohn's disease, suggest that bacterial uptake, rather than global dysbiosis, is the initiating factor

Immunology &Cell Biology, EarlyView.
To identify mechanisms underlying the earliest stages of disease initiation, we compared gene expression in aphthous ulcers, Peyer's patches, inflamed and endoscopically normal mucosa from patients and controls using total RNA‐seq. The signatures obtained suggest epithelial stress, plasma cell activation, monocyte activation and interferon‐γ signaling ...
Phillip J Whiley, Ojas VA Dixit, Mukta Das Gupta, Hardip Patel, Guoyan Zhao, Susan J Connor, Kim M Summers, David A Hume, Paul Pavli, Claire L O'Brien   +9 more
wiley   +1 more source