Results 11 to 20 of about 3,808 (149)
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran+16 more
wiley +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden+15 more
wiley +1 more source
Abstract Based on histological cross‐sections, the chondrocranium of the common musk turtle (Sternotherus odoratus) was reconstructed, described, and compared with other turtles. It differs from that of other turtle chondrocrania by possessing elongated, slightly dorsally orientated nasal capsules with three dorsolateral foramina, which might be ...
Luca Leicht+2 more
wiley +1 more source
The formate pseudo‐halide anion is strategically introduced at the buried interface to stabilize the intermediate phases formed during perovskite crystallization. The controlled crystallization enhances crystallinity and alleviates tensile strain, eliminating residual PbI2 near the buried interface.
Jongdeuk Seo+12 more
wiley +1 more source
Craniogenetic studies in Sus scrofa: With emphasis on the ‘orbitosphenoid’ problem
Abstract The orbitosphenoid is a skeletal element of the endocranium of extant mammals. However, it has also been described in many of their fossil ancestors. Craniogenetic studies show that it is composed of two types of bone: first, the cartilaginous ala orbitalis and parts of the trabecular plate are transformed by endochondral ossification; second,
Wolfgang Maier, Ulla Lächele, Irina Ruf
wiley +1 more source
This study introduces a scalable and colored low‐emissivity (low‐e) paint achieved by spraying an ultrathin n‐doped poly(benzodifurandione) (n‐PBDF) coating onto various colored substrates. The low‐e paint enhances thermal regulation by reducing mid‐infrared thermal emissivity to 0.19, thereby stabilizing indoor temperatures across diverse climates ...
Xiaojie Liu+13 more
wiley +1 more source
Phosphorescent OLEDs suffer from efficiency roll‐off due to triplet‐polaron quenching (TPQ). This study demonstrates for a large set of host‐guest combinations a spectroelectrochemical method to measure the absorption of charged molecules, enabling determining TPQ Förster radii (2.5–4 nm) from the spectral overlap.
Stan E. A. Jaspars+5 more
wiley +1 more source
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song+6 more
wiley +1 more source
This study investigates the plasmonic properties and biosensing capabilities of a nanocomposite incorporating Cu and Ag nanoparticles for detecting anti‐DbpA antibodies associated with Lyme disease. The enhanced LSPR response is explained through FDTD simulations of Cu–Ag near‐field interactions and increased surface roughness.
Sanjay Kumar+10 more
wiley +1 more source