Results 61 to 70 of about 32,387 (168)

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

open access: yesAdvanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang   +13 more
wiley   +1 more source

Design and Experimental Validation of a Photocatalyst Recommender Based on a Large Language Model

open access: yesAngewandte Chemie, EarlyView.
Choosing a photocatalyst for a given reaction can be challenging due to complex mechanisms and multiple parameters that govern the outcome of a photocatalyzed reaction. Herein, we disclose a machine learning (ML) model that can suggest catalysts for a given reaction using an online portal.
Francis Millward   +13 more
wiley   +2 more sources

Recent Progress in Mechanoluminescence for Multi‐Dimensional Stress Monitoring

open access: yesAdvanced Science, EarlyView.
Multi‐dimensional stress visualization technology (0D point detection, 1D linear distribution, 2D planar imaging, 3D volume reconstruction) has become a focus of attention in the field of stress sensing. The transition from “points” to “multi‐dimensional spatial fields” facilitates real‐time, in situ, and high‐resolution visualization of stress ...
Xiuxia Yang   +3 more
wiley   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

MXene‐Enhanced Electromembrane Systems for Advanced Water Applications: A Review

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
MXenes, synthesized via etching, intercalation, and delamination, exhibit hydrophilicity, conductivity, tunability, and strength, enabling roles as membranes, electrodes, and hybrids in electrical‐driven membrane technologies. These systems leverage adsorption, catalysis, separation, and self‐cleaning but face challenges in stability, scalability ...
Zainab Alansari   +2 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

Climate‐Smart Dairy Practices: The Role of Practice Clusters in Enhancing the Performance of Dairy Farms in Kenya

open access: yesAgribusiness, EarlyView.
ABSTRACT Climate variability is affecting the productivity, profitability, and resilience of smallholder dairy producers in developing countries. The adoption of climate‐smart (CS) dairy practices has been promoted to mitigate these negative effects. However, while interest in dairy CS practices is growing, empirical evidence on their adoption patterns
Mercy Mburu   +4 more
wiley   +1 more source

From Droplet to Diagnosis: Spatio‐Temporal Pattern Recognition in Drying Biofluids

open access: yesAdvanced Intelligent Systems, EarlyView.
This article integrates machine learning (ML) with the spatio‐temporal evolution of biofluid droplets to reveal how drying and self‐assembly encode distinctive compositional fingerprints. By leveraging textural features and interpretable ML, it achieves robust classification of blood abnormalities with over 95% accuracy.
Anusuya Pal   +2 more
wiley   +1 more source

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

open access: yesAnnals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang   +10 more
wiley   +1 more source

A Lightweight Skin‐Adhesive Fiber Bragg Grating Sensor to Advance Minimally Invasive Healthcare Monitoring

open access: yesAdvanced NanoBiomed Research, EarlyView.
A novel self‐adhesive hydrogel matrix is engineered to embed a fiber Bragg grating sensor for real‐time monitoring of physiological strain signals. The developed system conforms to the skin without external supports and, thanks to the fiber–matrix mechanical coupling, captures both subtle and large‐scale deformations.
Ilaria Condò   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy