Results 81 to 90 of about 29,802 (167)

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Regulation of working memory switches from striatal dopamine D2-receptor to D1-receptor neurons under high cognitive load. [PDF]

PLoS Biol
Chen XJ, Li F, Zhao X, Chen L, Xue J, Yao Z, Gan Z, Lian X, Liu Z, Tong L, Yan Q, Qiu L, Wang Q, Chen JF, Li Z.   +14 more
europepmc   +1 more source

Coordinated gene expression within sustained STAT3‐associated chromatin conformations contributes to hepatocellular carcinoma progression

Cancer Communications, EarlyView.
Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang, Sumin Yoon, Hyeokjun Yang, Nayun Choi, Su‐Hyang Han, Lark Kyun Kim, Hyoung‐Pyo Kim, Jong Hoon Park, Daeyoup Lee, Kyung Hyun Yoo   +9 more
wiley   +1 more source

Distinct role of claustrum and anterior cingulate cortex bidirectional circuits in methamphetamine taking and seeking. [PDF]

Nat Commun
Wu M, Lai M, Zhou Y, Cheng Y, Shi S, Wang F, Liu H, Zhao M, Zhou W.   +8 more
europepmc   +1 more source

Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases

ChemBioChem, Accepted Article.
The ubiquitin (Ub) system governs vital cellular processes in eukaryotic biology through an intricate network of Ub‐protein interactions. While semisynthetic C‐terminal Ub electrophiles (UbEs) are widely used to study Ub transfer and deubiquitinase (Dub) activity, they are limited to probing the active site while leaving other functionally important ...
Chittaranjan Das, Nipuni M. Pannala, Rishi S. Patel, Abhijith Saseendran Anit, Debapriya Bhattacharya, Kristos Negron Teron, Bryon Drown, Rudi Fasan   +7 more
wiley   +1 more source

Impact of a mineral enriched, fiber complex on glycaemic response and satiation in healthy adults: a double-blind, crossover intervention study. [PDF]

Eur J Nutr
Ancu O, Mackenzie RWA, Patterson M, Dsilva E, Yakubov GE, Haynes M, Kolida S, Stephenson CG, Costabile A.   +8 more
europepmc   +1 more source

Recent Progress in the Preparation of Graphdiyne‐Based Materials

ChemistryEurope, EarlyView.
Graphdiyne (GDY) has emerged as a versatile carbon allotrope for cutting‐edge applications. To fully unlock the distinguished characteristics of GDY‐based materials, precise preparation is vital for structure control, which largely shapes the materials’ properties.
Ruiqiao Wu, Xinlong Fu, Changshui Huang, Jingchi Gao, Jingxiang Yang, Yuliang Li   +5 more
wiley   +1 more source

Deciphering the history of ERK activity from fixed-cell immunofluorescence measurements. [PDF]

Nat Commun
Ram A, Pargett M, Choi Y, Murphy D, Teragawa C, Cabel M, Kosaisawe N, Quon G, Albeck JG.   +8 more
europepmc   +1 more source

Corn cob pyrolysis: A systematic literature review of methods and applications

The Canadian Journal of Chemical Engineering, EarlyView.
Mapping the research landscape of corn cob pyrolysis. Abstractas The agricultural sector is experiencing a surge in waste generation due to population growth, creating an urgent need to convert byproducts into value‐added products. Maize (Zea mays L.), a leading global crop, produces significant byproducts, such as corn cob, which are often undervalued.
Vilmar Steffen, Maiquiel Schmidt de Oliveira, Lais da Silva Pego Hericks, Schaline Winck Alberti, Marlon Henrique da Silva, Edson Antonio da Silva   +5 more
wiley   +1 more source

Lipoprotein(a) and Heart Failure Among Black and White Participants in Atherosclerosis Risk in Communities Study, Framingham Offspring Study, and Multi-Ethnic Study of Atherosclerosis: The Pooling Project. [PDF]

J Am Heart Assoc
Nomura S, Guan W, Zhang Y, Tison GH, Ikezaki H, Diffenderfer MR, Liu CT, Hoogeveen RC, Ballantyne CM, Schaefer EJ, Tsai MY.   +10 more
europepmc   +1 more source