Results 1 to 10 of about 517 (218)

Expression of the c-fos protooncogene by human and murine erythroblasts [PDF]

Blood, 1989
Abstract The expression of the c-fos protooncogene was investigated by in situ hybridization in normal murine bone marrow cells. A strong signal was found in murine marrow cells having the morphologic features of erythroblasts. This result was confirmed in human marrow cells using a double labeling technique (in situ hybridization and ...
J F, Caubet, M T, Mitjavila, A, Dubart, D, Roten, S C, Weil, W, Vainchenker   +5 more
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miR-146a targets c-Fos expression in human cardiac cells [PDF]

Disease Models & Mechanisms, 2015
miR-146a is a microRNA whose transcript levels are induced in the heart upon activation of NF-κB, a transcription factor induced by pro-inflammatory molecules strongly related to the pathogenesis of cardiac disorders. The main goal of this study consisted in studying new roles of miR-146a in cardiac pathological processes caused by the pro-inflammatory
Palomer, Xavier, Capdevila-Busquets, Eva, Botteri, Gaia, Davidson, Mercy M, Rodríguez, Cristina, Martínez-González, José, Vidal, Francisco, Barroso, Emma, Chan, Tung O, Feldman, Arthur M, Vázquez-Carrera, Manuel   +10 more
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The protooncogene c-fos is transcriptionally active in normal human granulocytes [PDF]

Blood, 1987
Abstract Total cellular RNA of highly purified normal human blood cell populations was analyzed for the expression of the protooncogene c-fos, the cellular counterpart of the transforming FBJ virus. In marked contrast to previous findings based on in vitro studies with permanent leukemic cell lines, c-fos transcription was restricted to ...
K, Heidorn, H, Kreipe, H J, Radzun, R, Müller, M R, Parwaresch   +4 more
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Expression of the proto-oncogene c-fos and the immunolocalization of c-fos, phosphorylated c-fos and estrogen receptor beta in the human testis.

Histology and histopathology, 2009
Spermatogenesis is under the control of a complex endocrine and paracrine system, including estrogen receptor (ER) signaling. In many target cells, ER promotes the transcription of c-fos and other proto-oncogenes to regulate cell growth and differentiation.
Araújo, Fabiano C., Oliveira, Cleida A., Reis, Augusto E., Del Puerto, Helen L., Martins, Almir S., Reis, Fernando M.   +5 more
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Fos and Jun Proteins Are Specifically Expressed During Differentiation of Human Keratinocytes [PDF]

Journal of Investigative Dermatology, 2005
Activator protein 1 (AP-1) proteins play key roles in the regulation of cell proliferation and differentiation. In this study we investigated the expression of Fos and Jun proteins in different models of terminal differentiation of human keratinocytes and in skin from psoriasis patients.
Mehic, Denis, Bakiri, Latifa, Ghannadan, Minoo, Wagner, Erwin F., Tschachler, Erwin   +4 more
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C-fos expression in vivo in human lymphocytes in response to stress

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1995
1. Blood samples from which lymphocytes were isolated were obtained from patients immediately prior to cardiac catheterization (stress period) and again four to five hours later (post-stress period). Blood was also taken from a normal non-stressed control subject. 2.
J E, Platt, X, He, D, Tang, J, Slater, M, Goldstein   +4 more
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Fos immunoreactivity assessment on human normal and pathological bronchial biopsies

Respiratory Medicine, 1995
The transcription factor Fos is involved in cell proliferation and differentiation. Its expression in normal and pathological adult human tissues and cells has rarely been studied. We therefore studied bronchial biopsies obtained from 14 normal subjects (NS), 18 non-steroid-treated asthmatics, 10 corticosteroid-treated asthmatics and 10 patients with ...
Demoly, P., Chanez, P., Pujol, J-L., Gauthier-Rouvière, C., Michel, F-B., Godard, P., Bousquet, J.   +6 more
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Tissue-specific expression of mRNA in mouse lymphocytes detected by v-fos but not by human c-fos CNA probes.

Cell Structure and Function, 1990
Transcription of the c-fos gene is known to be induced transiently by many types of cellular stimuli in various cultured cell lines; however, several authors have reported that the c-fos gene is constitutively transcribed in lymphoid cells. We detected, in fact, abundant transcripts which hybridized with a v-fos DNA probe in nuclear run-off transcripts
Kikuchi, Keiji, Makishima, Fusao
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Functional dissection in vitro of the human c-fos promoter.

Journal of Biological Chemistry, 1991
Using internal and 5' deletions, the elements contributing to the in vitro activity of the human c-fos promoter have been identified. Wild type and mutant promoters were fused to the G-free cassette and tested, using HeLa nuclear and whole cell extracts, with the fos wild type promoter as the internal control.
R A, Hipskind, A, Nordheim
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Glucocorticoids decrease c-fos expression in human nasal polyps in vivo [PDF]

Thorax, 1998
Activated c-fos binds to jun proteins to form the activation protein 1 (AP-1) transcription factor that regulates cytokine and other proinflammatory genes. c-Fos may play a key role in nasal polyp formation. Glucocorticoids may exert their anti-inflammatory effects through an interaction of glucocorticoid receptors with AP-1 that leads to mutual ...
J N, Baraniuk, G, Wong, M, Ali, M, Sabol, T, Troost   +4 more
openaire   +2 more sources