Results 81 to 90 of about 517 (218)

Rats respond to aversive emotional arousal of human handlers with the activation of the basolateral and central amygdala. [PDF]

Proc Natl Acad Sci U S A, 2023
Kaźmierowska AM, Kostecki M, Szczepanik M, Nikolaev T, Hamed A, Michałowski JM, Wypych M, Marchewka A, Knapska E.   +8 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

The growth factor FGF21 maintains neuromuscular junction through histone deacetylase HDAC4 in denervation-induced skeletal muscle atrophy. [PDF]

J Biol Chem
Zheng L, Sasaki T, Ni L, Hashidume T, Kawabe M, Takahashi Y, Yamauchi Y, Shimizu M, Sato R.   +8 more
europepmc   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Psychometric properties of the Feedback Orientation Scale in the clinical workplace of health professions students. [PDF]

Int J Med Educ
Fuentes-Cimma J, Sluijsmans D, Perez-Mejias P, Villagran I, Riquelme A, Heeneman S.   +5 more
europepmc   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Effect of a fructooligosaccharides fraction from <i>Psacalium decompositum</i> on the intestinal bacterial microbiota of rats. [PDF]

Biosci Microbiota Food Health
Juárez-Pérez MG, Alarcón-Aguilar FJ, Jasso-Villagómez JI, Canales-Martínez MM, Campos-Contreras JE, Escalona-Buendía H, Fernández FJ.   +6 more
europepmc   +1 more source

COL1A1+ Epithelial Cells Orchestrate VEGFA‐VEGFR Signaling in Endometritis Revealed by Single‐Cell Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
Single‐cell RNA‐seq of normal and endometritis endometrium shows reduced epithelial cells and fate divergence toward ferroptosis or ribosome/antigen‐presentation programs. COL1A1+ epithelial cells act as an AP‐1–driven hub that enhances VEGFA–VEGFR signaling and remodels the vascular microenvironment.
Chengzi Tian, Zaiyi Li
wiley   +1 more source

The evolution of interdisciplinarity and internationalization in scientific journals. [PDF]

Elife
Zhou H, Nunes Amaral LA.
europepmc   +1 more source

Macroscopic, Histological and Ultrastructural Features of the Tongue of the Anatolian Wild Boar (Sus scrofa libycus)

Microscopy Research and Technique, EarlyView.
Integrated macroscopic, histological, and ultrastructural analyses revealed five distinct lingual papillae types (filiform, fungiform, conical, foliate, and vallate) in the Anatolian wild boar (Sus scrofa libycus). Mechanical papillae showed marked structural specialization, while gustatory papillae exhibited region‐specific distribution of taste buds.
Fatma Işbilir, Banu Kandil, Muhammed Zahid Atli, İhsan Işbilir, Barış Can Güzel   +4 more
wiley   +1 more source