Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu +5 more
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GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian models. [PDF]
Baumer-Harrison C +18 more
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Zhang J +10 more
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Bettadapura SS +9 more
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Koton S +19 more
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