Results 131 to 140 of about 7,543 (166)

It started off as a Cys, how did it end up like this? Identifying the extent of unmodelled oxidatively modified cysteines within the Protein Data Bank

Acta Crystallographica Section D, EarlyView.
This work examines data contained within 118 215 structures in the Protein Data Bank for unmodelled difference density concomitant with unmodelled oxidatively damaged cysteines. This analysis demonstrates that site‐specific oxidation of residues is a phenomenon of which the experimenter should be aware, and highlights the need for a suitable detection ...
Samuel P. Foster, Anna J. Warren, C. Alistair Siebert, Jaswir Basran, Peter C. E. Moody   +4 more
wiley   +1 more source

The prefrontal cortex controls memory organization in the hippocampus. [PDF]

Nat Neurosci
de Sousa AF, Zeidler ZE, Almeida-Filho DG, Shen Y, Luchetti A, Simanian S, Mardini M, DeNardo LA, Silva AJ.   +8 more
europepmc   +1 more source

Unusual backfolded binding poses of BAZ2A bromodomain binders

Acta Crystallographica Section D, EarlyView.
We identified BAZ2A‐binding compounds assuming a peculiar, almost enclosed, conformation. These molecules pose a basis for the development of potent BAZ2A macrocyclic inhibitors, as performed for other bromodomains.BAZ2A is a large multidomain protein overexpressed in aggressive prostate cancer, where it potentiates migration and invasion of other ...
Andrea Dalle Vedove, Giulia Cazzanelli, Vito Giuseppe D'Agostino, Pablo Andres Vargas Rosales, Amedeo Caflisch, Graziano Lolli   +5 more
wiley   +1 more source

Social touch-like tactile stimulation alleviates stress-induced anxiety-like behavior by enhancing the oxytocin level in the prefrontal cortex. [PDF]

Neurobiol Stress
Liu M, Ying L, Luo H, Huang P, Chen W, Wu J.   +5 more
europepmc   +1 more source

‘Mere Amateurs’? Elementary Teachers and the Making of Scientific Authority in the British Child Study Movement

History, EarlyView.
Abstract This article offers new perspectives on the relationship between elementary teaching, scientific expertise and the professionalization of the human sciences. Previous scholarship has demonstrated the ready existence of ‘amateur’ science societies in the nineteenth century where cross‐class exchanges were common.
Julia Gustavsson
wiley   +1 more source

One-year multicenter surveillance of Fosfomycin resistance Enterobacterales: the rise of FosA3-producing <i>P. mirabilis</i>. [PDF]

Curr Res Microb Sci
Chudejova K, Mattioni Marchetti V, Zaccaria V, Kanova S, Sramkova A, Krutova M, Ryskova L, Kroneislova G, Horvathova B, Tejkalova R, Krejci E, Vagnerova I, Zemanova Z, Bitar I.   +13 more
europepmc   +1 more source

Sino‐Mexican Encounters Before the ‘Diplomatic Opening’: Exhibition Diplomacy and Grassroots Friendship in the 1960s

History, EarlyView.
Abstract During the 1960s, Mexico's Institutional Revolutionary Party (PRI) embraced Chinese overtures for a commercial opening as consistent with its anti‐imperialist posture, thereby foreshadowing the diplomatic opening to China in 1972. Yet this professed ideological pluralism was eclipsed by an underlying allegiance to the United States' anti ...
YIXIN TIAN
wiley   +1 more source

The ventral hippocampus to paraventricular thalamus circuit regulates context-dependent hyperlocomotion through PAC1 receptor signaling in the chronic stress-induced PTSD mouse model. [PDF]

Transl Psychiatry
Cao Z, Gao H, Tang B, Xu Y.
europepmc   +1 more source

‘The Tragedy of a Small Nation’: Alexander Devine and British Perspectives on the Montenegrin Question, 1918–24

History, EarlyView.
Abstract This article examines the pro‐Montenegrin political campaigns of Alexander Devine, a schoolmaster and journalist who became Montenegro's leading British advocate following its incorporation into the Kingdom of Serbs, Croats and Slovenes after the First World War.
ROSS CAMERON
wiley   +1 more source

Pupillometry and brain-wide c-Fos mapping uncover multimodal mirror emotional contagion related networks of mice. [PDF]

iScience
Caldarelli M, Zucca S, Viglione A, Stella A, Nisar R, Sagona G, Papini EM, Carrara F, Bovetti S, Mazziotti RM, Pizzorusso T.   +10 more
europepmc   +1 more source