Results 61 to 70 of about 263,880 (288)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Editorial: Foster Care and Development

open access: yesSocial Work and Society, 2017
Foster Care Research in Europe is extremely diverse. Traditionally, it has been strongly informed by psychology, especially attachment theory, as well as by therapeutic initiatives and psychopathology.
Daniela Reimer   +3 more
doaj   +2 more sources

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey   +2 more
wiley   +1 more source

Examining universal access to acute hospital care in Ireland during the first three months of COVID-19: Lessons from the policy process [version 1; peer review: 2 approved]

open access: yesHRB Open Research
Background The onset of the COVID-19 pandemic prompted the Irish state to address unprecedented challenges by prioritising public health and equitable access to care.
Sarah Parker   +2 more
doaj   +1 more source

Adolescents in Foster Care: Emotional Environment in Foster Families

open access: yesПсихологическая наука и образование, 2018
The article reveals the specifics of professional activities of specialists that support foster families taking care of adolescents.The outcomes of our study allow us to compare the emotional environment in foster families and families of origin (birth ...
Shulga T.I., , Antipina M.A.,
doaj   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Foster care: motivations and challenges for foster families

open access: yesSocial Work and Society, 2017
The article focuses on the experience of foster care as reported by a group of foster parents involved in a research study in a Province of the Northern Italy. The Province, which provides foster care services and supports the local services, carried out
Cinzia Canali   +2 more
doaj   +2 more sources

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