Results 31 to 40 of about 927,942 (314)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Finding Adoptive/Foster Families for Children with Disabilities Using Social Media - the Voice of Professionals

open access: yesLubelski Rocznik Pedagogiczny, 2022
Introduction: Creating families for children with disabilities is more difficult than for non-disabled children due to the smaller number of willing candidates for adoptive/ foster parents.
Urszula Bartnikowska
doaj   +1 more source

Analysis of professionals and family foster care on advantages and difficulties of visits between foster children and their biological families [PDF]

open access: yes, 2016
Contact between a foster child and birth parents play an important role in relation to the foster child’s wellbeing. The main aim of this study is to give voice to social workers and foster families about contact visits.
Bernedo-Muñoz, Isabel Maria   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Experiences of Emergency Foster Carers in Creating a Child-Safe Environment

open access: yesSocialinis Darbas: Patirtis ir Metodai, 2021
Recently, a lot of attention has been paid to the implementation of child wel¬fare in Lithuania: in mid-2018 the reform of child protection was launched. As the result of these reforms, taking a child from parents became not only difficult, but as a last
Julija Eidukevičiūtė   +1 more
doaj   +1 more source

“My children are my world” : Raising the voices of birth mothers with substantial experience of counselling following the loss of their children to adoption or foster care [PDF]

open access: yes, 2019
There is very little published literature on ‘what works’ in terms of support for birth mothers following the loss of their children to compulsory adoption or foster care.
Morgan, Hannah   +3 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

SPECIAL FEATURES OF CHILDRENPARENTS RELATIONS IN FOSTER FAMILIES

open access: yesВестник Кемеровского государственного университета, 2014
The paper discusses the results of a study of parent-child relationships in foster care. The differences in the types of motivation adoption are revealed.
I. S. Morozova, K. N. Belogay, T. O. Ott
doaj  

California Youth Transitions to Adulthood Study (CalYOUTH): Early Findings from the Child Welfare Worker Survey [PDF]

open access: yes, 2015
This report presents findings from the Child Welfare Worker Survey, an on-line survey of 235 California child welfare workers and their perceptions of key characteristics of the service delivery context of extended foster care, including: the ...
Katherine Halsted   +3 more
core  

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