Results 21 to 30 of about 4,240,673 (310)

Acolhimento de crianças e adolescentes em situações de abandono, violência e rupturas Fostering children and adolescents in situations of abandonment, violence and separation

Psicologia: Reflexão e Crítica, 2012
A proteção integral à infância encontra-se em reordenamento. Baseadas nas experiências do GIAAA-CINDEDI (Grupo de Investigação sobre Abrigamento, Acolhimento Familiar e Adoção - Centro de Investigações sobre Desenvolvimento Humano e Educação Infantil ...
Maria Clotilde Rossetti-Ferreira, Ivy Gonçalves de Almeida, Nina Rosa do Amaral Costa, Lilian de Almeida Guimarães, Fernanda Neísa Mariano, Sueli Cristina de Pauli Teixeira, Solange Aparecida Serrano   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Adolescents in Foster Care: Emotional Environment in Foster Families

Психологическая наука и образование, 2018
The article reveals the specifics of professional activities of specialists that support foster families taking care of adolescents.The outcomes of our study allow us to compare the emotional environment in foster families and families of origin (birth ...
Shulga T.I., , Antipina M.A.,
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Family Foster Care Coordinator and His Role in Foster Care System

Lubelski Rocznik Pedagogiczny, 2018
The purpose of the article is the discussion about new profession – family foster care coordinator. The author presents work dimensions of the foster care coordinator which results both from statutory assumptions and those related to tasks that go beyond
Tomasz Gebel
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

REGIONAL EXPERIENCE IN ORGANIZING KINSHIP (FAMILY) CARE FOR THE ELDERLY AND DISABLED

Векторы благополучия: экономика и социум, 2022
The relevance of the research topic is determined by the increase in the number of elderly and disabled people in Russia and around the world, including those who need constant long-term care, as well as an increase in the burden on inpatient social ...
Evgeniya G. Kopalkina, Anastasia I. Gulyaeva   +1 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

The child and the family in frames of activities of Barnavernet organization. An attempt of evaluation from the Polish and Norwegian perspective [PDF]

Studia z Teorii Wychowania, 2019
In the article, the author raises controversial questions concerning the functioning of the Norwegian institution Barnavernet, seen from both Polish and Norwegian perspectives.
Elżbieta Czykwin
doaj   +1 more source