Results 81 to 90 of about 1,645,835 (250)

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

Bridges between families. Contact and its meaning for foster children, foster parents and birth families

open access: yesSocial Work and Society, 2017
Contacts between foster children and their birth families are an essential element of a foster care relationship. (Direct) contacts create a connection between the children and their birth families and often pose a challenge to all involved.
Carmen Hofer-Temmel
   +1 more
doaj   +2 more sources

Foster parents’ experiences with animal companions while fostering children and youth

open access: yesHuman-Animal Interactions
This qualitative exploratory inquiry examined foster parents’ perspectives of the impact companion animals had on the children/youth in their care. Six foster parents were interviewed and six themes, including 12 subthemes, were uncovered: (1) provision ...
Jeanette Wiens, T. Pearson, C. Whalen
doaj   +1 more source

Toward Material‐Specific Peptides From in Silico Guided Peptide Engineering to Target PET in the Presence of PS

open access: yesAdvanced Science, EarlyView.
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka   +3 more
wiley   +1 more source

Examining the Impact of COVID-19 on Parental Stress: A Study of Foster Parents. [PDF]

open access: yesChild Adolesc Social Work J, 2022
Miller JJ, Cooley ME, Mihalec-Adkins BP.
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

Opportunities and Barriers in the Partnership Between Foster Families and Schools

open access: yesCentral European Journal of Educational Research
The primary socialisation area is the family, and the secondary socialisation area is educational institutions.  From the point of view of educational sociology, the meeting between the family and the school institution represents the intersection of ...
Nóra Kocsis
doaj   +1 more source

Posttraumatic stress in preschool children in foster care : The influence of the foster parents [PDF]

open access: yes, 2017
Introduction. It can be argued that preschool children in foster care are at high risk for developing posttraumatic stress disorder (PTSD) and further mental health problems as consequence of the high exposure to potentially traumatic events.
Vasileva, Mira
core  

Home - About - Disclaimer - Privacy