Results 91 to 100 of about 9,399,244 (284)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A study on Strengthening of Building foundation for Storey Extension
Journal of Building Materials and Structures, 2019 Storey extensions are an increasingly popular way to crowded cities. Lack experience and knowledge concerning strengthening of structures are major challenges for engineers.
Magdi M. E. Zumrawi, Hiba K. E. Aldawi
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Corporate Forms Facilitating Non-Profit Networking: Formalizing the Informal
Baltic Journal of Law & Politics, 2017 Cooperation and networking among a variety of organisations for the purpose of research, projects, and other activities ranges from ad hoc to long term organisational relationships, formalised or based on informal cooperation.
Jakulevičienė Lyra, Valutytė Regina
doaj +1 more source
Discrete model of the pile foundation
Инженерно-строительный журнал, 2015 The solid pile foundation is modeled by elastic vertical bars distributed over the area of the base in a uniform grid. It was assumed that the body of the structure is rigid, its weight is offset from the geometric center.
M.N. Kirsanov
doaj +1 more source
Home Depot Foundation - 2009 Annual Report [PDF]
, 2010 Contains videos of president's message, 2008 highlights, and national impact; program information; grantee profiles; grant information by state; awards; and lists of corporate donors, board members, staff, and supplier advisory committee ...
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Health of the individual, of the family, of society
Social MedicineTwenty-one years ago the Pioneer Health Centre housing the Peckham Experiment, closed. During twelve working years it explored the nature of health and had devised a method for its scientific investigation. Since that time the particular contribution the
The Pioneer Health Foundation
doaj
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source