Results 121 to 130 of about 10,675,039 (377)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Corrigendum

open access: yesConcussion, 2020
The Drake Foundation
doaj   +1 more source

Gauge and Lorentz Transformation Placed on the Same Foundation [PDF]

open access: gold, 2011
Rein Saar   +3 more
openalex   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Mausoleum of the XIV century in the southern part of the Bolgar settlement (excavation trench CLXXIV). Research 2012

open access: yesПоволжская археология, 2014
The results of archaeological studies on the remains of a stone mausoleum, discovered in the southern part of the Bulgar fortified settlement site in 2012 are published.
Elkina Irina I.
doaj  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Vision–language foundation model for echocardiogram interpretation

open access: yesNature Medicine
The development of robust artificial intelligence models for echocardiography has been limited by the availability of annotated clinical data. Here, to address this challenge and improve the performance of cardiac imaging models, we developed EchoCLIP, a
M. Christensen   +3 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Numerical investigation of non-overflow section stability

open access: yesWater Science
Constructing dams is one of the human achievements in developing urban societies. In the last few decades, rapid growth in developing the Red Sea coast and Sinai in Egypt has taken place.
Mohamed Yosry Rezk   +3 more
doaj   +1 more source

Frey Foundation - 2006 Annual Report [PDF]

open access: yes, 2006
Contains grants list, grantee profiles, photographs, and financial ...

core  

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