Results 231 to 240 of about 10,675,039 (377)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Optical heterostructure in a two-dimensional organic crystal. [PDF]

Nat Commun
Liao K, Zhang J, Yu XL, Xu W, Xia Z, Zhou D, Mao Z, Lv Y, Ming Y, Liu C, Sheng M, Liu K, Zhang Z, Zhu C, Wang X, Zhu C, An Z, Wang L.   +17 more
europepmc   +1 more source

The Universal Gravito–Informational Theory (TGIU): Core Framework and Foundational Equations of Informational Curvature

Sebastian Virtosu
openalex   +1 more source

Foundation for Change: Affording Chevron Deference to Substantive IRS Notices

, 2012
Ryan Hilleshiem
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Plan meta-objective for sub-micron quantitative phase imaging. [PDF]

Light Sci Appl
Wang J, Sun J, Li J, Huang C, Ji J, Shen W, Wang Z, Zhou J, Chen C, Zhu S, Li T.   +10 more
europepmc   +1 more source

Beyond the Intervention Gap: The Mechanics of the 02$ Matrix and Foundational Resilience via the Sovereign Stability Index (SSI)

Mandeep Singh
openalex   +1 more source

Improving overall moisture content of friction yarn for its use in foundation garments – part 2

, 2019
Kanwar Varinder Pal Singh, Apurba K. Das, Raúl Fangueiro   +2 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Three-Dimensional Reconstruction and Scour Volume Detection of Offshore Wind Turbine Foundations Based on Side-Scan Sonar. [PDF]

Sensors (Basel)
Wang Y, Tao L, Yuan M, Yang J.
europepmc   +1 more source