Results 71 to 80 of about 9,399,244 (284)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
McKnight Foundation - 2008 Annual Report [PDF]
Contains mission statement, program information, grant and project highlights, financial statements, and lists of board members and staff.
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Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Women & Children Living in Poverty [PDF]
Produced by the WNY Women\u27s Foundation in August 2017, this fact sheet details information and statistics about women and children experiencing poverty in ...
WNY Women\u27s Foundation
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Starting from the historical and epistemological problem of “visibility”, this article discusses the role and authority of “experience” in the field of (feminist) history and historiography. The article criticizes the foundational function of “experience”
Joan Wallach Scott
doaj +1 more source
Highlights of the Foundation Center's 1997 Study: International Grantmaking - A Report on U.S. Foundation Trends [PDF]
A comprehensive review of trends in international grantmaking has never been undertaken. This study fills that gap for one important source of private support—U.S. grantmaking foundations. The study was conducted by the Foundation Center with the support
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

