Results 141 to 150 of about 4,219,089 (361)

Effectiveness of an e-learning course in evidence-based medicine for foundation (internship) training [PDF]

open access: bronze, 2010
Julie Hadley   +20 more
openalex   +1 more source

Easy Innovation and the Iron Cage: Best Practice, Benchmarking, Ranking, and the Management of Organizational Creativity [PDF]

open access: yes, 2003
The use of what came to be known as best practices, benchmarking, and ranking, which took corporate America by storm in the 1980s as a method for managing innovation, has seeped into government and nonprofit organizations in the intervening years.
H. George Frederickson
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

The Importance Of Community: Investing In Effective Community-Based Crime Prevention Strategies [PDF]

open access: yes, 2015
After more than a year of listening to our community, researching evidence-based practices, and evaluating our own efforts, 'The Importance of Community' inaugural report unequivocally asserts that our greatest potential of reducing homicides and ...
Roderick D. S. Wheeler
core  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Access to Diagnostics and Treatment for People With Metastatic EGFR-Positive NSCLC: Lessons From Project PRIORITY

open access: yesJTO Clinical and Research Reports
Introduction: The treatment landscape for people diagnosed with EGFR-mutated (EGFR-m) NSCLC has rapidly evolved, yet there remains limited self-reported information about the lived experience.
Jill Feldman, MA   +8 more
doaj  

Going Beyond H&E and Oncology: How Do Histopathology Foundation Models Perform for Multi-stain IHC and Immunology? [PDF]

open access: yesarXiv
This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including ImageNet-pretrained networks, and histopathology foundation models trained on both public and proprietary data, on ...
arxiv  

Anatomy of an Almshouse Complex [PDF]

open access: yes, 2013
The focus of this paper is to determine the age and function of a partial building foundation uncovered during archaeological testing in City Hall Park, New York City.
Baugher, Sherene, Lenik, Edward J.
core   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

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