Results 121 to 130 of about 2,460,880 (358)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Yawkey Foundations 2010 Grants Report [PDF]
, 2011 Contains mission statement, board chair and president's message; grantee profiles in the areas of health, education, and human services; 2010 grants list and highlights; grant guidelines; and list of board ...
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
International Archives of OtorhinolaryngologyIntroduction The Otorhinolaryngology Foundation (FO), created in 1995, has played an important role in the advancement of otorhinolaryngology in Brazil, through initiatives in education, research, and service provision.
Ricardo Ferreira Bento +4 more
doaj +1 more source
FROM WINKLER’S FOUNDATION TO POPOV’S FOUNDATION
Facta Universitatis, Series: Mechanical Engineering, 2019 In recent years, the method of dimensionality reduction (MDR) has started to figure as a very convenient tool for dealing with a wide class of elastic contact problems. The MDR modeling framework introduces an equivalent punch profile and a one-dimensional Winkler-type elastic foundation, called henceforth Popov’s foundation.
openaire +5 more sources
Topological Foundations of Cognitive Science [PDF]
, 1984 A collection of papers presented at the First International Summer Institute in Cognitive Science, University at Buffalo, July 1994, including the following papers: ** Topological Foundations of Cognitive Science, Barry Smith
Eschenbach, Carola +2 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Interaction Design: Foundations, Experiments [PDF]
, 2006 Interaction Design: Foundations, Experiments is the result of a series of projects, experiments and curricula aimed at investigating the foundations of interaction design in particular and design research in general.
Hallnäs, Lars, Redström, Johan
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source