Results 221 to 230 of about 2,433,140 (357)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
The cognitive foundations of STEM achievement: a cross-national multilevel and SEM investigation. [PDF]
Front PsycholMetli A.
europepmc +1 more source
Preventing Terrorists’ Misuse of Charitable Foundations: A Situational Crime Prevention Approach
, 2019 Garnadi Walanda, Muhamad Syauqillah
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
The Zeus Action: Variational Foundations of Curvature–Entropy Recursive Dynamics
Nick Brown, Alexander
openalex +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Foundations of Emergency Medicine: Application of a Flipped-Classroom Curriculum for Advanced Practice Clinician Education. [PDF]
West J Emerg MedLindsey S +5 more
europepmc +1 more source