Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Will online behavioral research follow the fate of online survey research? [PDF]
Van der Stigchel S +3 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Multiscale Structural Modulation and Synergistic Enhancement of Transparency and Relaxor Behavior in La3+-Doped KNN Lead-Free Ceramics. [PDF]
Yang X +8 more
europepmc +1 more source
Advaita Chakra Theory I: Microscopic Foundations of a Single-Sector Chakra Substrate
Rajendran, Praveen Kizhakkeveedu
openalex +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Correction: Reclaiming human dignity: a critical review of contemporary theories in light of ontological foundations. [PDF]
Frantz P, Rego F, Barbas S.
europepmc +1 more source
Quantum Portfolio Management (QPM): Foundations in Motion
Corella Nieto, Kevin
openalex +1 more source
The Foundations of the Cleft Palate Center and Training Program at the University of Illinois
Samuel Pruzansky
openalex +2 more sources
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

