Results 81 to 90 of about 168,192,818 (226)

Boston University School of Medicine catalog [PDF]

open access: yes, 1894
Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core  

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

open access: yesAdvanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu   +17 more
wiley   +1 more source

Catalog: Boston University School of Medicine, School of Public Health [PDF]

open access: yes, 1981
Viewbook/course catalog of the Boston University School of Public Health.Program description & applications ...
Boston University School of Public Health
core  

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li   +15 more
wiley   +1 more source

Catalog: Boston University School of Medicine, School of Public Health [PDF]

open access: yes, 1988
Viewbook/course catalog of the Boston University School of Public Health.Program descriptions, application ...
Boston University School of Public Health
core  

Unifying Composition and Process Design: A Heterogeneous Graph Neural Network for Discovering High‐Performance Cu Alloys

open access: yesAdvanced Science, EarlyView.
By overcoming the fixed‐path limitations of conventional machine learning, a heterogeneous graph neural network fundamentally reconstructs material data representation. Integrating variable processing sequences with intrinsic elemental features, this framework enables exploratory optimization across high‐dimensional spaces.
Jie Yin   +12 more
wiley   +1 more source

Boston University School of Medicine catalog [PDF]

open access: yes, 1881
Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core  

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

open access: yesAdvanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu   +12 more
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

Ru‐Doping‐Engineered Oxygen Vacancies in MoO3‐x Nanostructured Films With Ultrahigh Capacitance for Flexible Asymmetric Supercapacitors

open access: yesAdvanced Science, EarlyView.
Ru‐doping‐induced defect engineering enables freestanding Ru–MoO3‐x flexible films with enriched oxygen vacancies, modulated band structure, and enhanced charge transport. The optimized electrode delivers ultrahigh capacitance approaching the theoretical limit of MoO3, while assembled asymmetric supercapacitors exhibit high energy density, wide‐voltage
Xiaoqing Bin   +8 more
wiley   +1 more source

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