Results 41 to 50 of about 1,024 (212)

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source

Floral morphology and embryo sac development in Burretiodendron kydiifolium Y. C. Hsu et R. Zhuge (Tiliaceae) and their systematic significance

, 1998
Floral morphology and development of megaspore and megagametophyte in Burretiodendron kydiifolium are described. The ovule is anatropous, crassinucellate and bitegmic. The archesporium is multicellular and usually two cells develop to megasporocytes. The
Tang, YA, Int Ctr Integrated Mt Dev, GPO Box 3226, Kathmandu, Nepal., Tang, YA   +1 more
core  

Embryo sac development in Stellaria media

, 2014
Osmiophilic granules were observed during certain stages of intermitotic periods in one, two and four nucleate embryo sacs in Stellaria media. The granules, some inside the short ER cisternae, were mainly distributed along the walls of nucleate embryo ...
Bohdan Rodkiewicz, Mieczysław Kuraś, Krystyna Kudlicka   +2 more
core   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Floral development and anatomy of pistillate flowers of Lophophytum (Balanophoraceae), with special reference to the embryo sac inversion

, 2016
The extreme reduction of flowers in the Balanophoraceae has generated few and incomplete studies with scattered and often contradictory results with respect to embryology.
González, Ana María, Sato, Héctor Arnaldo   +1 more
core   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Embryo Sac Formation in Allium thunbergii, with Transmission Electron Microscope Observation [PDF]

application/pdfThe development of embryo sac in Allium thumbergii was investigated using a light and an electron microscope. Two ovules, which are composed of a thin curved nucellus invested with two integuments, are formed in each of three ovarian ...
Shioyama, Kayoko, Kirito, Eimi, Sato, Yoshihiko   +2 more
core   +1 more source

Development of wild-type female gametophyte.

, 2013
A. A female gametophyte at FG1 showing functional megaspore (M) and degenerated megaspores (DM). B. A female gametophyte at FG2 with one nucleus at the chalazal pole (ChN), and the other nucleus at the micropylar pole (MN). The degenerated megaspores (DM)
Dong-Qiao Shi (326679), Jie Liu (15128), Yan-Ping Long (326680), Si-Qi Wang (127881), Wei-Cai Yang (326681)   +4 more
core   +1 more source