Results 61 to 70 of about 8,586,817 (317)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Quaternion Electromagnetism and the Relation with 2-Spinor Formalism
, 2019 By using complex quaternion, which is the system of quaternion representation extended to complex numbers, we show that the laws of electromagnetism can be expressed much more simply and concisely.
Hong, I. K., Kim, C. S.
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Optimized Forest-Ruth- and Suzuki-like algorithms for integration of motion in many-body systems
, 2001 An approach is proposed to improve the efficiency of fourth-order algorithms for numerical integration of the equations of motion in molecular dynamics simulations.
Allen +22 more
core +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Gravito-electromagnetism versus electromagnetism
, 2003 The paper contains a discussion of the properties of the gravito-magnetic interaction in non stationary conditions. A direct deduction of the equivalent of Faraday-Henry law is given.
A Tartaglia +20 more
core +2 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Cosmic-ray hydrodynamics: Alfv\'en-wave regulated transport of cosmic rays
, 2019 Star formation in galaxies appears to be self-regulated by energetic feedback processes. Among the most promising agents of feedback are cosmic rays (CRs), the relativistic ion population of interstellar and intergalactic plasmas.
Pfrommer, Christoph, Thomas, Timon
core +1 more source
Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
A Wearable Gait Phase Detection System Based on Force Myography Techniques
Italian National Conference on Sensors, 2018 (1) Background: Quantitative evaluation of gait parameters can provide useful information for constructing individuals’ gait profile, diagnosing gait abnormalities, and better planning of rehabilitation schemes to restore normal gait pattern.
Xianta Jiang +3 more
semanticscholar +1 more source