Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Simulation Study on Driving Force Distribution Pattern and Four-wheel Independent Drive System
In order to improve the efficiency of driving force and the control ability of special vehicle,dynamic performance and stability,the distribution pattern of the four-wheel independent drive system is studied.
Chi Peng, Wang Shukun
doaj
Theoretical model of driving force for variable geometry hypersonic inlet based on principle of virtual work [PDF]
To enable hypersonic inlets to operate across a wide Mach number range, the geometric configuration of the inlet must be adjusted. The magnitude of the driving force required to actuate these geometric changes is fundamental to the design of the inlet ...
Jia Cai +6 more
doaj +1 more source
Dissipative Particle Dynamics Simulations for Phospholipid Membranes Based on a Four-To-One Coarse-Grained Mapping Scheme. [PDF]
In this article, a new set of parameters compatible with the dissipative particle dynamics (DPD) force field is developed for phospholipids. The coarse-grained (CG) models of these molecules are constructed by mapping four heavy atoms and their attached ...
Xiaoxu Li, Lianghui Gao, Weihai Fang
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Quaternion Electromagnetism and the Relation with 2-Spinor Formalism
By using complex quaternion, which is the system of quaternion representation extended to complex numbers, we show that the laws of electromagnetism can be expressed much more simply and concisely.
Hong, I. K., Kim, C. S.
core +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source
Investigation on Motorcyclist Riding Behaviour at Curve Entry Using Instrumented Motorcycle
This paper details the study on the changes in riding behaviour, such as changes in speed as well as the brake force and throttle force applied, when motorcyclists ride over a curve section road using an instrumented motorcycle.
Choon Wah Yuen +2 more
doaj +1 more source
The Electromagnetic Unification of Four Forces and Electromagnetic Structures of Particles
Recently, the book “Electromagnetic Unification of Four Forces” (ISBN978-3-659-76798-2) was published, compiling the progressions in physics made by the world people, manifested in television while led notably by me and the Members in the world satellite networks from India, Zhejiang and USA.
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source

