Results 71 to 80 of about 724,876 (319)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Theoretical model of driving force for variable geometry hypersonic inlet based on principle of virtual work [PDF]
AIP AdvancesTo enable hypersonic inlets to operate across a wide Mach number range, the geometric configuration of the inlet must be adjusted. The magnitude of the driving force required to actuate these geometric changes is fundamental to the design of the inlet ...
Jia Cai +6 more
doaj +1 more source
Dissipative Particle Dynamics Simulations for Phospholipid Membranes Based on a Four-To-One Coarse-Grained Mapping Scheme. [PDF]
PLoS ONE, 2016 In this article, a new set of parameters compatible with the dissipative particle dynamics (DPD) force field is developed for phospholipids. The coarse-grained (CG) models of these molecules are constructed by mapping four heavy atoms and their attached ...
Xiaoxu Li, Lianghui Gao, Weihai Fang
doaj +1 more source
Quaternion Electromagnetism and the Relation with 2-Spinor Formalism
, 2019 By using complex quaternion, which is the system of quaternion representation extended to complex numbers, we show that the laws of electromagnetism can be expressed much more simply and concisely.
Hong, I. K., Kim, C. S.
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Simulation Study on Driving Force Distribution Pattern and Four-wheel Independent Drive System
Jixie chuandong, 2018 In order to improve the efficiency of driving force and the control ability of special vehicle,dynamic performance and stability,the distribution pattern of the four-wheel independent drive system is studied.
Chi Peng, Wang Shukun
doaj
Extra force in $f(R)$ modified theories of gravity
, 2007 The equation of motion for test particles in $f(R)$ modified theories of gravity is derived. By considering an explicit coupling between an arbitrary function of the scalar curvature, $R$, and the Lagrangian density of matter, it is shown that an extra ...
Christian G. Böhmer +6 more
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
, 2006 We have investigated the proof of the $H$ theorem within a manifestly covariant approach by considering the relativistic statistical theory developed in [G. Kaniadakis, Phy. Rev. E {\bf 66}, 056125, 2002; {\it ibid.} {\bf 72}, 036108, 2005].
Abe +24 more
core +2 more sources