Results 71 to 80 of about 8,037,396 (263)
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Brownian Motion in Robertson-Walker Space-Times from electromagnetic Vacuum Fluctuations
We consider classical particles coupled to the quantized electromagnetic field in the background of a spatially flat Robertson-Walker universe. We find that these particles typically undergo Brownian motion and acquire a non-zero mean squared velocity ...
Carlos H. G. Béssa +3 more
core +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Tribological Studies Regarding the Crude Rapeseed Oil Press
The aim of this paper is to present a tribology test conducted on crude rapeseed oil press. The experiments were carried out with four-ball machine. The oil was tested at speed of 1000 rot/min and loads of 140 N and 200 N.
Liviu Cătălin ŞOLEA
doaj
In this study, we developed a new force plate system. Conventional force plates output force and moment by using the signals of three-axis load cells. The developed force plate installs four 5-axis load cells, and each load cell can output 3-axis force ...
Kiyoshi Hirose, Akiko Kondo
doaj +1 more source
A General Relativistic Rotating Evolutionary Universe
We show that when we work with coordinate cosmic time, which is not proper time, Robertson-Walker's metric, includes a possible rotational state of the Universe. An exact formula for the angular speed and the temporal metric coefficient, is found.Comment:
C. Brans +7 more
core +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Theoretical model of driving force for variable geometry hypersonic inlet based on principle of virtual work [PDF]
To enable hypersonic inlets to operate across a wide Mach number range, the geometric configuration of the inlet must be adjusted. The magnitude of the driving force required to actuate these geometric changes is fundamental to the design of the inlet ...
Jia Cai +6 more
doaj +1 more source

