ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Copas-Heckman-Type Sensitivity Analysis for Publication Bias in Rare-Event Meta-Analysis Under Generalized Linear Mixed Models. [PDF]
Zhou Y +5 more
europepmc +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Assessment of SARS-CoV-2 genome sequence recovery from four lateral flow device products available in the UK. [PDF]
Lewandowski K +10 more
europepmc +1 more source
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Bridging the gap in PCNL preoperative planning: software-free stone metrics that outperform conventional measures. [PDF]
Wei B, Ning F, Fu Y, Ji L, Gu S, Wang Y.
europepmc +1 more source
A sustainability-oriented supply chain supplier selection framework using resilience and HSE performance metrics in the automotive industry. [PDF]
Maddah S +5 more
europepmc +1 more source
A Factor Analysis of the COMFORTneo Scale: What Are We Measuring? [PDF]
Koning E +4 more
europepmc +1 more source
Neuroimmune dysregulation and comorbidity mechanisms of major depressive disorder and migraine. [PDF]
Liang G +11 more
europepmc +1 more source
Individual work performance questionnaire: Translation and validation in Chinese. [PDF]
Tang G, Omar S, Abu Bakar R.
europepmc +1 more source

