Results 41 to 50 of about 713,528 (258)
Four- and three-body channel coupling effects on 6Li elastic scattering with CDCC
EPJ Web of Conferences, 2016 We investigate breakup dynamics in 6Li elastic scattering on heavy targets (T = 209Bi or 208Pb) near the Coulomb barrier energy. Since the subsystem of 6Li has a bound state as deuteron (n + p = d), a four-body channel (6Li + T → n + p + α + T) and a ...
Watanabe Shin +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Development of Four-Channel Buck-Type LED Driver with Automatic Current Sharing
Energies, 2021 A buck-type light-emitting diode (LED) driver is proposed herein. The proposed LED driver automatically possesses current sharing and high step-down voltage gain. Without complex control, the proposed LED driver, with a single input and multiple outputs,
Yeu-Torng Yau, Kuo-Ing Hwu, Yao-De Tsai
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Hungarian Geographical Bulletin, 2017 Over the past years, the concept of 'Central Europe' has been revived by Hungarian political elites and this study aims to find out how and why. It is based on a content analysis of political speeches and communications, compared with actual policies and
Péter Balogh
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Compact Four-Channel Optical Emission Module with High Gain
PhotonicsIn this paper, a four-channel optical emission module is developed using hybrid integration technology that integrates directly modulated laser (DML) chips, low-noise amplifier (LNA) chips, and control circuits, with dimensions of 24.4 mm × 21 mm × 5.9 ...
Xiying Dang +6 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source