Results 31 to 40 of about 824,025 (319)

Noninvasive Optical Imaging of Ovarian Metastases Using Cy5-labeled RAFT-c(-RGDfK-)

Molecular Imaging, 2006
Our group has developed a new molecular tool based on the use of a regioselectively addressable, functionalized template (RAFT) scaffold, where four cyclic (Arg-Gly-Asp) (cRGD) peptide motifs were grafted.
Zhao-hui Jin, Veronique Josserand, Jesus Razkin, Elisabeth Garanger, Didier Boturyn, Marie-Christine Favrot, Pascal Dumy, Jean-luc Coll   +7 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Shape Classification using Multiscale Fourier-based Description in 2-D Space [PDF]

, 2008
In shape recognition, the boundary and exterior parts are amongst the most discriminative features. In this paper, we propose new multiscale Fourier-based object descriptors in 2-D space, which represents the boundary and exterior parts of an object more
Cem Direkoglu, Mark S. Nixon, Nixon, Mark S., Direkoglu, Cem   +3 more
core   +1 more source

A new dye uptake assay to test the activity of antibioticsagainst intracellular Francisella tularensis

Frontiers in Cellular and Infection Microbiology, 2014
Francisella tularensis, a facultative intracellular bacterium, is the aetiological agent of tularaemia. Antibiotic treatment of this zoonosis is based on the administration of a fluoroquinolone or a tetracycline for cases with mild to moderate severity ...
Vivien eSutera, Vivien eSutera, Yvan eCaspar, Yvan eCaspar, Sandrine eBoisset, Sandrine eBoisset, Max eMaurin, Max eMaurin   +7 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

ADN « environnemental » : un saut méthodologique pour les inventaires de la biodiversité [PDF]

Sciences, Eaux & Territoires, 2012
Utilisée en France pour réaliser l’inventaire de la grenouille taureau dans le cadre d’un programme d’éradication de cette espèce envahissante, la méhode de l'ADNe a montré des résultats encourageants pour détecter l’espèce dans des sites où elle est ...
MIAUD, Claude, TABERLET, Pierre, TABERLET, Pierre   +2 more
doaj  

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Manganese Cytotoxicity Assay on Hippocampal Neuronal Cell Culture

Bio-Protocol, 2015
Compared to an in vivo experiment, neuronal cell cultures are immediately accessible to observation and manipulation. In this protocol, we describe a technique to evaluate the cytotoxicity of a metal, manganese (Mn2+), on hippocampal neuronal cell ...
Alexia Daoust, Yasmina Saoudi, Jacques Brocard, Nora Collomb, Cécile Batandier, Mariano Bisbal, Murielle Salomé, Annie Andrieux, Sylvain Bohic, Emmanuel Barbier   +9 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source